From the Departments of *Radiology, and †Nuclear Medicine, the Affiliated Hospital of Sichuan Medical University, Luzhou, Sichuan, People's Republic of China.
Clin Nucl Med. 2016 Mar;41(3):209-10. doi: 10.1097/RLU.0000000000001075.
An 18-year-old man with progressive headache and vomiting for 2 weeks had significantly elevated levels of WBC count, which kept on rising over time during in-hospital evaluation. Exhaustive examinations did not reveal infection or any other explanations of increased WBC count. Instead, brain MRI and FDG PET/CT identified a malignant lesion in the brain without abnormality elsewhere. The pathological examination revealed a rhabdoid meningioma. The level of the WBC counts returned to normal promptly after surgical resection of the tumor, which confirmed the diagnosis of paraneoplastic leukemoid reaction.
一位 18 岁男性,因进行性头痛和呕吐 2 周就诊,入院评估期间白细胞计数持续显著升高。详尽的检查并未发现感染或其他导致白细胞计数升高的原因。相反,脑部 MRI 和 FDG PET/CT 显示脑部存在恶性病变,而其他部位无异常。病理检查显示为横纹肌样脑膜瘤。肿瘤切除术后,白细胞计数迅速恢复正常,明确了副肿瘤性类白血病反应的诊断。