Klipa T V, Eremenko A A, Shepelyuk A N, Antonov I O
Anesteziol Reanimatol. 2015 Jul-Aug;60(4):43-9.
This literature review is devoted to modern condition of pharmacological neuroprotection. Aeuroprotection as a complex method of brain protection and reduction of neurological complications is a relevant trend in practical anesthesia and intensive care. The following data represents frequency of neurological complications in different types of surgery and its main classifications. In the first part of the review potential neuroprotectional abilities of modern anesthesia medications are discussed Mechanisms of neuronal destruction and possible ways of impact on the pathophysiological processes via pharmacological agents are observed. The most promising drugs with neuroprotectional effects are selected. In the second part of the review we are going to examine neuroprotection effects of non-anesthetic drugs.
这篇文献综述致力于药理学神经保护的现代状况。神经保护作为一种脑保护和减少神经并发症的综合方法，是临床麻醉和重症监护中的一个相关趋势。以下数据展示了不同类型手术中神经并发症的发生率及其主要分类。在综述的第一部分，讨论了现代麻醉药物潜在的神经保护能力，观察了神经元破坏的机制以及通过药物作用于病理生理过程的可能方式，并挑选出了最具前景的具有神经保护作用的药物。在综述的第二部分，我们将研究非麻醉药物的神经保护作用。
