Tsimmerman Ya S
Klin Med (Mosk). 2015;93(7):5-14.
Modern data on primary biliary liver cirrhosis are presented including the definition, prevalence, possible etiological factors, and detailed description of pathogenesis (autoimmune mechanisms, intrahepatic cholestasis, hereditary predisposition, environmental factors) and clinical picture. Also considered are complications and concomitant diseases, methods of laboratory, instrumental and morphological diagnostics, approaches to medicamental treatment and its effectiveness, indications for liver transplantation.
本文介绍了原发性胆汁性肝硬化的现代数据，包括定义、患病率、可能的病因、发病机制（自身免疫机制、肝内胆汁淤积、遗传易感性、环境因素）的详细描述以及临床表现。还讨论了并发症和伴发疾病、实验室、仪器和形态学诊断方法、药物治疗方法及其有效性、肝移植指征。
