Gerdt A M, Shutov A M, Menzorov M V, Naydenova V V
Klin Med (Mosk). 2015;93(7):50-5.
to estimate the frequency and severity of acute kidney injury (AKI) in patients with stroke and the influence of AKI on intra-hospital lethality.
180 patients with stroke. 8 (4.4%) of them died within 24 hr after admission. It was impossible to diagnose AKI in these patients from serum creatinine dynamics. The development of AKI was followed up in the remaining 80 (47.1%) men and 91 (52.9%) women (mean age 66.6 ± 11.2 yr). AKI was diagnosed and classified as recommended by KDIGO (2012).
AKI was documented in 47 (27.3%) patients including 13 (41.9%) and 34 (24.1%) with hemorrhagic and ischemic stroke respectively. Logistic regressive analysis revealed association of in-hospital lethality with AKI (relative risk 2.5; 95%, CI 1.7-3.8) regardless of sex, age, stroke type, duration of the disease prior to hospitalisation, arterial hypertension, and diabetes.
stroke is complicated by AKI in every fourth patient; in combination, they significantly increase intra-hospital lethality.
评估卒中患者急性肾损伤（AKI）的发生率和严重程度以及AKI对院内死亡率的影响。
180例卒中患者。其中8例（4.4%）在入院后24小时内死亡。根据血清肌酐动态变化无法在这些患者中诊断AKI。对其余80例（47.1%）男性和91例（52.9%）女性（平均年龄66.6±11.2岁）随访AKI的发生情况。AKI的诊断和分类按照KDIGO（2012）的建议进行。
47例（27.3%）患者记录有AKI，其中分别有13例（41.9%）出血性卒中和34例（24.1%）缺血性卒中患者发生AKI。逻辑回归分析显示，无论性别、年龄、卒中类型、入院前疾病持续时间、动脉高血压和糖尿病情况如何，院内死亡率与AKI相关（相对风险2.5；95%可信区间1.7 - 3.8）。
每四分之一的卒中患者会并发AKI；二者并存会显著增加院内死亡率。
