人下颌下腺匀浆对4-雄烯-3,17-二酮的体外代谢
In vitro metabolism of 4-androstene-3,17-dione by human submaxillary gland homogenates.
作者信息
Coffey J C, Crutchfield W C
出版信息
J Dent Res. 1977 Mar;56(3):332-4. doi: 10.1177/00220345770560032101.
PMID:265963
Abstract
Tritiated 4-androstene-3,17-dione was incubated with human submaxillary gland homogenates. In 180-minute incubations, human submaxillary gland converted 4-androstene-3,17-dione predominately to testosterone and to a lesser extent, 5alpha-androstane-3alpha,17beta-diol and androsterone.
摘要
将氚标记的4-雄烯-3,17-二酮与人颌下腺匀浆一起孵育。在180分钟的孵育过程中，人颌下腺将4-雄烯-3,17-二酮主要转化为睾酮，其次转化为5α-雄烷-3α,17β-二醇和雄甾酮。
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