Hanci D, Ulusoy S, Muluk N B, Cingi C
B-ENT. 2015;11(3):211-8.
To investigate the role of viral infection in benign paroxysmal positional vertigo (BPPV).
In this retrospective study, 483 patients with BPPV were included in the study group. The control group consisted of 461 healthy subjects. In both groups, serologic analysis of viral agents (HSV1, HSV2, Herpes zoster, EBV, CMV, adenovirus, influenza, and parainfluenza virus) was performed.
With the exception of influenza and parainfluenza, all viral serology values were higher in the BBPV group than the control group. We also observed seasonal variation. The BPPV group exhibited elevated values for HSV1 and adenovirus in March and May, for Herpes zoster, adenovirus, and influenza in April, for HSV1 in June, and for HSV1 and CMV in September, compared to the control group. In October, the BPPV group showed increased values for all of the viruses studied, compared to the control group.
BPPV is associated with positive viral serology, particularly during certain months of the year, mainly in spring and autumn. Viral infection might promote BPPV attacks due to the development of vestibulopathy or induce secondary BPPV via viral infection-related neurolabyrinthitis.
探讨病毒感染在良性阵发性位置性眩晕（BPPV）中的作用。
在这项回顾性研究中，研究组纳入了483例BPPV患者。对照组由461名健康受试者组成。对两组进行病毒病原体（HSV1、HSV2、带状疱疹病毒、EB病毒、巨细胞病毒、腺病毒、流感病毒和副流感病毒）的血清学分析。
除流感病毒和副流感病毒外，BPPV组的所有病毒血清学值均高于对照组。我们还观察到了季节性变化。与对照组相比，BPPV组在3月和5月HSV1和腺病毒值升高，4月带状疱疹病毒、腺病毒和流感病毒值升高，6月HSV1值升高，9月HSV1和巨细胞病毒值升高。10月，与对照组相比，BPPV组所有研究病毒的值均升高。
BPPV与病毒血清学阳性有关，特别是在一年中的某些月份，主要是在春季和秋季。病毒感染可能由于前庭病变的发展而促进BPPV发作，或通过病毒感染相关的神经迷路炎诱发继发性BPPV。
