Kumar Dhivya Ashok, Agarwal Amar, Sivanganam Soundari, Chandrasekar Radika
From Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
From Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
J Cataract Refract Surg. 2015 Sep;41(9):1945-53. doi: 10.1016/j.jcrs.2015.01.020.
To analyze the functional and anatomic outcomes of management of Descemet membrane detachment after phacoemulsification using a protocol based on the detachment's height, extent, and chord length and its relation to the pupil.
Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
Prospective comparative case series.
Eyes with post-phacoemulsification Descemet membrane detachment were managed surgically or medically based on the detachment's height, extent, length (chord), and relation to the pupil (HELP protocol). Central corneal thickness (CCT), chord length, and detachment height were determined by anterior segment optical coherence tomography (AS-OCT) (Visante).
Of 161 eyes, 96 were treated surgically (Group 1) and 65 medically (Group 2). The mean length and mean height of Descemet membrane detachment were 2.4 mm ± 1.4 (SD) and 266 ± 189.8 μm, respectively, in Group 1 and 1.03 ± 0.4 mm and 153.3 ± 60.8 μm, respectively, in Group 2. The complete reattachment rate was 95.8% in Group 1 and 96.9% in Group 2. The corrected distance visual acuity (CDVA) was 20/40 or better in 83.3% of eyes in Group 1 and 92.3% of eyes in Group 2. No eye lost CDVA as a result of a Descemet membrane scar in the central 5.0 mm of the cornea. The AS-OCT allowed visualization of the detachment in all eyes with a CCT of more than 800 μm. There was no difference in the final CDVA between Group 1 and Group 2.
The AS-OCT-based algorithm was effective for managing post-surgical Descemet membrane detachment in eyes with dense corneal edema. Early surgical intervention for detachments in the central cornea can reduce scarring-induced visual loss.
No author has a financial or proprietary interest in any material or method mentioned.
采用基于后弹力层脱离高度、范围、弦长及其与瞳孔关系的方案,分析白内障超声乳化术后后弹力层脱离的功能和解剖学转归。
印度钦奈阿加瓦尔眼科医院及眼科研究中心。
前瞻性比较病例系列。
对白内障超声乳化术后发生后弹力层脱离的患眼,根据脱离的高度、范围、长度(弦长)及其与瞳孔的关系(HELP方案)进行手术或药物治疗。通过眼前节光学相干断层扫描(AS-OCT)(Visante)测定中央角膜厚度(CCT)、弦长和脱离高度。
161只眼中,96只接受手术治疗(第1组),65只接受药物治疗(第2组)。第1组后弹力层脱离的平均长度和平均高度分别为2.4 mm±1.4(标准差)和266±189.8μm,第2组分别为1.03±0.4 mm和153.3±60.8μm。第1组的完全复位率为95.8%,第2组为96.9%。第1组83.3%的患眼和第2组92.3%的患眼矫正远视力(CDVA)达到20/40或更好。没有患眼因角膜中央5.0 mm范围内的后弹力层瘢痕而导致CDVA下降。CCT大于800μm的所有患眼中,AS-OCT均可显示脱离情况。第1组和第2组的最终CDVA无差异。
基于AS-OCT的算法对于处理角膜重度水肿患眼的术后后弹力层脱离有效。对中央角膜脱离进行早期手术干预可减少瘢痕引起的视力丧失。
无作者对文中提及的任何材料或方法存在财务或专利权益。