Bhandari Suryaprakash, Maydeo Amit
Baldota Institute of Digestive Sciences, Global Hospitals, 35, Dr. E. Borges Road, Parel East, Opp Shirodkar High School, Mumbai, 400 012, India.
Indian J Gastroenterol. 2015 Nov;34(6):458-62. doi: 10.1007/s12664-015-0614-z. Epub 2015 Nov 26.
Majority of the bile duct stones (BDS) are radiolucent (RL) and are amenable to conventional endoscopic extraction techniques. There is no publication that specifically discusses the optimal management of radio-opaque (RO) BDS and makes a distinction from the strategy followed for RL BDS.
Data of patients with BDS managed endoscopically from January 2009 till June 2015 were retrospectively reviewed. Diagnosis of RO stone was established during initial fluoroscopy, just prior to obtaining a cholangiogram. Endoscopic retrograde cholangiopancreatography (ERCP) was done using therapeutic duodenoscope. Stone extraction was attempted initially using conventional techniques. Balloon sphincteroplasty or mechanical lithotripsy (ML) or both were done if conventional techniques failed. Cholangioscopy-guided intracorporeal holmium laser lithotripsy (LL) was done when all the above techniques failed.
Fifteen patients were found to have RO stones in the bile duct during the study period. ERCP was successful in all patients. Discrepancy of the stone size in relation to the lower CBD diameter was seen in eight patients (53.34 %). Stone extraction with conventional techniques was successful in 2/15 patients (13 %). Successful controlled radial expansion (CRE) balloon sphincteroplasty/ML was possible in 5/15 patients (33 %). Cholangioscopy guided LL was done in eight patients (53.34 %) with successful pulverization of RO BDS (100 %).
RO bile duct stones provide unique challenges for endoscopic management with success of conventional techniques in only about half of them (46 %). RO stones detected on fluoroscopy are extremely hard and difficult to crush with lithotripsy basket probably due to high calcium content. Cholangioscopy guided LL provides an excellent alternative management strategy.
大多数胆管结石(BDS)是透X线的(RL),适合采用传统的内镜下取石技术。目前尚无专门讨论不透X线(RO)BDS的最佳治疗方法并与RL BDS所采用策略进行区分的文献发表。
回顾性分析2009年1月至2015年6月接受内镜治疗的BDS患者的数据。RO结石的诊断在初始荧光透视检查时,即在获得胆管造影之前确定。使用治疗性十二指肠镜进行内镜逆行胰胆管造影(ERCP)。最初尝试使用传统技术取石。如果传统技术失败,则进行球囊括约肌成形术或机械碎石术(ML)或两者同时进行。当上述所有技术均失败时,进行胆管镜引导下体内钬激光碎石术(LL)。
在研究期间,发现15例患者胆管内有RO结石。所有患者的ERCP均成功。8例患者(53.34%)的结石大小与胆总管下段直径存在差异。15例患者中有2例(13%)采用传统技术成功取石。15例患者中有5例(33%)成功进行了可控径向扩张(CRE)球囊括约肌成形术/ML。8例患者(53.34%)进行了胆管镜引导下的LL,RO BDS成功粉碎(100%)。
RO胆管结石给内镜治疗带来了独特的挑战,传统技术仅在约一半(46%)的患者中取得成功。荧光透视检查发现的RO结石极其坚硬,可能由于钙含量高而难以用碎石篮粉碎。胆管镜引导下的LL提供了一种出色的替代治疗策略。