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经内镜胆道大球囊扩张碎石术治疗巨大嵌顿结石:西方系列研究。

Endoscopic Biliary Large Balloon Dilation Lithotripsy for Giant and Impacted Stones Removal: A Western Series.

机构信息

Endoscopy Division, Department of Gastroenterology, Federal University of Health Sciences of Porto Alegre / Santa Casa Hospital, Porto Alegre, Brazil.

Endoscopy Division, Department of Gastroenterology, Federal University of Health Sciences of Porto Alegre / Santa Casa Hospital, Porto Alegre, Brazil,

出版信息

Dig Dis. 2021;39(4):391-398. doi: 10.1159/000511766. Epub 2020 Sep 22.

Abstract

BACKGROUND

Endoscopic removal of packed, large, or impacted stones, in which a basket cannot be deployed or is unable to grasp the stone(s), is challenging and inevitably leads to repeated procedures such as stent insertion and extra- or intracorporal lithotripsy. In this study, we describe the results of an alternative stone disintegration technique in a considerable series of patients using an esophageal/pyloric balloon for stone fragmentation or making working space in the bile duct to allow the deployment of the basket, a technique we call endoscopic biliary large balloon lithotripsy.

METHODS

We retrieved data from 1,429 endoscopic retrograde cholangiopancreatographies (ERCPs) from 2 prospective trials performed between 2014 and 2019. Patients with difficult bile duct stones, in which a balloon dilator up to 15 mm was used to crush or increase the working space parallel to the stones in the common or hepatic duct, were included in the study.

RESULTS

From the 1,429 ERCPs, 299 had difficult stones (>1 cm, impacted or multiple stones). Large balloon lithotripsy was employed in 46 cases after endoscopic papillotomy and endoscopic biliary large balloon dilation with failed attempted balloon or basket stone(s) extraction. Failure to clear the bile duct at first ERCP occurred in 4 cases (91.3% of success). Complications were observed in 5 patients (10.8%; 1 perforation, 1 pancreatitis, and 3 bleedings), who were treated conservatively.

CONCLUSIONS

Large balloon lithotripsy, in order to crush the stones or make working room for baskets or balloons in the bile duct, is an effective, safe, and low cost technique for impacted, packed, or giant bile duct stones.

摘要

背景

对于已包裹、较大或嵌顿的结石,如果无法使用篮筐或篮筐无法抓取结石,则进行内镜下取石具有挑战性,不可避免地会导致反复进行支架置入和额外或体内碎石等操作。在本研究中,我们描述了在相当多的患者中使用食管/幽门球囊进行结石碎裂或在胆管中制造工作空间以允许篮筐部署的替代结石碎裂技术的结果,我们称之为内镜胆道大球囊碎石术。

方法

我们从 2014 年至 2019 年进行的 2 项前瞻性试验中检索了 1429 例内镜逆行胰胆管造影术(ERCP)的数据。纳入研究的患者为胆管结石困难,即使用最大至 15mm 的球囊扩张器平行于胆总管或肝内胆管的结石进行碎石或增加工作空间。

结果

在 1429 例 ERCP 中,有 299 例为困难性结石(>1cm,嵌顿或多发结石)。在经内镜乳头切开术和内镜胆道大球囊扩张后,对于未能成功尝试提取球囊或篮筐结石的 46 例患者,采用大球囊碎石术。首次 ERCP 未能清除胆管的情况发生在 4 例患者中(成功率为 91.3%)。5 例患者(10.8%)出现并发症(1 例穿孔,1 例胰腺炎,3 例出血),均给予保守治疗。

结论

为了粉碎结石或为胆管中的篮筐或球囊制造工作空间,大球囊碎石术是一种有效、安全且低成本的治疗嵌顿、包裹或巨大胆管结石的技术。

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