Vesey Alex T, Dweck Marc R, Fayad Zahi A
British Heart Foundation Centre for Cardiovascular Science, College of Medicine and Veterinary Medicine, University of Edinburgh, Room Suite 305, The Chancellor's Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK.
British Heart Foundation Centre for Cardiovascular Science, College of Medicine and Veterinary Medicine, University of Edinburgh, Room Suite 305, The Chancellor's Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK; Imaging Science Laboratories, Department of Radiology, Translational and Molecular Imaging Institute, Mount Sinai School of Medicine, 1 Gustave L. Levy Place, New York, NY 10029, USA; Imaging Science Laboratories, Department of Medicine, Translational and Molecular Imaging Institute, Mount Sinai School of Medicine, 1 Gustave L. Levy Place, New York, NY 10029, USA.
Neuroimaging Clin N Am. 2016 Feb;26(1):55-68. doi: 10.1016/j.nic.2015.09.005.
By harnessing the versatility and soft tissue imaging capabilities of MR imaging alongside the unmatched sensitivity and biomolecular flexibility of PET, the potential to provide detailed multiparametric plaque characterization in the carotid arteries is clear. The ability to acquire simultaneous, and dynamic multimodal data is perhaps PET/MR's greatest strength that will be of major interest to researchers investigating carotid and coronary atherosclerosis alike. This review summarizes the current status of dedicated hybrid PET/MR imaging; to crystallize the rationale for and advantages of this technique with respect to carotid atherosclerosis; and to discuss current limitations, challenges, and future directions.
通过利用磁共振成像（MR成像）的多功能性和软组织成像能力，以及正电子发射断层扫描（PET）无与伦比的灵敏度和生物分子灵活性，在颈动脉中提供详细的多参数斑块特征的潜力是显而易见的。获取同步动态多模态数据的能力可能是PET/MR最大的优势，这将引起研究颈动脉和冠状动脉粥样硬化的研究人员的极大兴趣。本综述总结了专用混合PET/MR成像的现状；明确该技术在颈动脉粥样硬化方面的原理和优势；并讨论当前的局限性、挑战和未来方向。
