Roxbury Christopher R, Ishii Masaru, Gallia Gary L, Reh Douglas D
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, 601 North Caroline Street, 6th Floor, Baltimore, MD 21287, USA.
Department of Neurosurgery, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Phipps Building, Room 101, Baltimore, MD 21287, USA.
Otolaryngol Clin North Am. 2016 Feb;49(1):153-65. doi: 10.1016/j.otc.2015.09.010.
Esthesioneuroblastoma is a rare malignant tumor of sinonasal origin. These tumors typically present with unilateral nasal obstruction and epistaxis, and diagnosis is confirmed on biopsy. Over the past 15 years, significant advances have been made in endoscopic technology and techniques that have made this tumor amenable to expanded endonasal resection. There is growing evidence supporting the feasibility of safe and effective resection of esthesioneuroblastoma via an expanded endonasal approach. This article outlines a technique for endoscopic resection of esthesioneuroblastoma and reviews the current literature on esthesioneuroblastoma with emphasis on outcomes after endoscopic resection of these malignant tumors.
嗅神经母细胞瘤是一种起源于鼻窦的罕见恶性肿瘤。这些肿瘤通常表现为单侧鼻塞和鼻出血，活检可确诊。在过去15年中，内镜技术取得了重大进展，使这种肿瘤适合扩大经鼻内切除术。越来越多的证据支持通过扩大经鼻内入路安全有效地切除嗅神经母细胞瘤的可行性。本文概述了嗅神经母细胞瘤的内镜切除技术，并回顾了目前关于嗅神经母细胞瘤的文献，重点是这些恶性肿瘤内镜切除后的结果。
