• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

一种用于电磁导航超声支气管镜检查（EBUS）的新型平台。

A novel platform for electromagnetic navigated ultrasound bronchoscopy (EBUS).

作者信息

Sorger Hanne, Hofstad Erlend Fagertun, Amundsen Tore, Langø Thomas, Leira Håkon Olav

机构信息

Department of Thoracic Medicine, St. Olavs Hospital, Postboks 3250, Sluppen, 7006, Trondheim, Norway.

Department of Circulation and Medical Imaging, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), AHL-senteret, Prinsesse Kristinas gate 3, Trondheim, Norway.

出版信息

Int J Comput Assist Radiol Surg. 2016 Aug;11(8):1431-43. doi: 10.1007/s11548-015-1326-7. Epub 2015 Nov 28.

DOI:10.1007/s11548-015-1326-7
PMID:26615428
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4958402/
Abstract

PURPOSE

Endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) of mediastinal lymph nodes is essential for lung cancer staging and distinction between curative and palliative treatment. Precise sampling is crucial. Navigation and multimodal imaging may improve the efficiency of EBUS-TBNA. We demonstrate a novel EBUS-TBNA navigation system in a dedicated airway phantom.

METHODS

Using a convex probe EBUS bronchoscope (CP-EBUS) with an integrated sensor for electromagnetic (EM) position tracking, we performed navigated CP-EBUS in a phantom. Preoperative computed tomography (CT) and real-time ultrasound (US) images were integrated into a navigation platform for EM navigated bronchoscopy. The coordinates of targets in CT and US volumes were registered in the navigation system, and the position deviation was calculated.

RESULTS

The system visualized all tumor models and displayed their fused CT and US images in correct positions in the navigation system. Navigating the EBUS bronchoscope was fast and easy. Mean error observed between US and CT positions for 11 target lesions (37 measurements) was [Formula: see text] mm, maximum error was 5.9 mm.

CONCLUSION

The feasibility of our novel navigated CP-EBUS system was successfully demonstrated. An EBUS navigation system is needed to meet future requirements of precise mediastinal lymph node mapping, and provides new opportunities for procedure documentation in EBUS-TBNA.

摘要

目的

纵隔淋巴结的支气管内超声引导经支气管针吸活检（EBUS-TBNA）对于肺癌分期以及区分根治性和姑息性治疗至关重要。精确采样至关重要。导航和多模态成像可能会提高EBUS-TBNA的效率。我们在专用气道模型中展示了一种新型的EBUS-TBNA导航系统。

方法

使用带有用于电磁（EM）位置跟踪的集成传感器的凸探头EBUS支气管镜（CP-EBUS），我们在模型中进行了导航CP-EBUS操作。术前计算机断层扫描（CT）和实时超声（US）图像被整合到一个用于EM导航支气管镜检查的导航平台中。CT和US容积中目标的坐标在导航系统中进行配准，并计算位置偏差。

结果

该系统可视化了所有肿瘤模型，并在导航系统中正确的位置显示了它们融合的CT和US图像。操作EBUS支气管镜快速且容易。11个目标病变（37次测量）的US和CT位置之间观察到的平均误差为[公式：见原文]毫米，最大误差为5.9毫米。

结论

我们新型的导航CP-EBUS系统的可行性得到了成功证明。需要一种EBUS导航系统来满足未来精确纵隔淋巴结定位的要求，并为EBUS-TBNA中的操作记录提供新的机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/33350925f5d9/11548_2015_1326_Fig12_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/5a3820730f76/11548_2015_1326_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/9eb49240fb24/11548_2015_1326_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/53cfc7787309/11548_2015_1326_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/0de98cffb733/11548_2015_1326_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/a6953e9290cf/11548_2015_1326_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/2a1e94118b37/11548_2015_1326_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/1cbd1adceaf2/11548_2015_1326_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/ac0041b2d4fe/11548_2015_1326_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/5c50460ff1e4/11548_2015_1326_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/784eafd6a7d4/11548_2015_1326_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/16f015ff9879/11548_2015_1326_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/33350925f5d9/11548_2015_1326_Fig12_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/5a3820730f76/11548_2015_1326_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/9eb49240fb24/11548_2015_1326_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/53cfc7787309/11548_2015_1326_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/0de98cffb733/11548_2015_1326_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/a6953e9290cf/11548_2015_1326_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/2a1e94118b37/11548_2015_1326_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/1cbd1adceaf2/11548_2015_1326_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/ac0041b2d4fe/11548_2015_1326_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/5c50460ff1e4/11548_2015_1326_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/784eafd6a7d4/11548_2015_1326_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/16f015ff9879/11548_2015_1326_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7481/4958402/33350925f5d9/11548_2015_1326_Fig12_HTML.jpg

相似文献

1
A novel platform for electromagnetic navigated ultrasound bronchoscopy (EBUS).一种用于电磁导航超声支气管镜检查（EBUS）的新型平台。
Int J Comput Assist Radiol Surg. 2016 Aug;11(8):1431-43. doi: 10.1007/s11548-015-1326-7. Epub 2015 Nov 28.
2
A multimodal image guiding system for Navigated Ultrasound Bronchoscopy (EBUS): A human feasibility study.一种用于导航超声支气管镜检查（EBUS）的多模态图像引导系统：一项人体可行性研究。
PLoS One. 2017 Feb 9;12(2):e0171841. doi: 10.1371/journal.pone.0171841. eCollection 2017.
3
Combined endobronchial and esophageal endosonography for the diagnosis and staging of lung cancer: European Society of Gastrointestinal Endoscopy (ESGE) Guideline, in cooperation with the European Respiratory Society (ERS) and the European Society of Thoracic Surgeons (ESTS).支气管内与食管内超声联合用于肺癌诊断及分期：欧洲胃肠内镜学会（ESGE）指南，与欧洲呼吸学会（ERS）及欧洲胸外科医师学会（ESTS）合作制定
Endoscopy. 2015 Jun;47(6):545-59. doi: 10.1055/s-0034-1392040. Epub 2015 Jun 1.
4
Navigated ultrasound bronchoscopy with integrated positron emission tomography-A human feasibility study.导航超声支气管镜检查与正电子发射断层扫描集成——一项人体可行性研究。
PLoS One. 2024 Aug 30;19(8):e0305785. doi: 10.1371/journal.pone.0305785. eCollection 2024.
5
Endobronchial ultrasound convex-probe transbronchial needle aspiration as the first diagnostic test in patients with pulmonary masses and associated hilar or mediastinal nodes.经支气管超声凸面探头经支气管针吸活检术作为肺部肿块伴肺门或纵隔淋巴结肿大患者的首选诊断性检查。
Intern Med J. 2009 Jul;39(7):435-40. doi: 10.1111/j.1445-5994.2008.01731.x. Epub 2008 Jun 28.
6
Endobronchial ultrasonography for positron emission tomography and computed tomography-negative lymph node staging in non-small cell lung cancer.支气管内超声在非小细胞肺癌正电子发射断层扫描和计算机断层扫描阴性淋巴结分期中的应用
Ann Thorac Surg. 2014 Nov;98(5):1762-7. doi: 10.1016/j.athoracsur.2014.05.078. Epub 2014 Aug 20.
7
Real-time endobronchial ultrasound-guided transbronchial needle aspiration of mediastinal and hilar lymph nodes.实时支气管内超声引导下纵隔及肺门淋巴结经支气管针吸活检术
Chest. 2004 Jul;126(1):122-8. doi: 10.1378/chest.126.1.122.
8
Endobronchial ultrasound-guided transbronchial needle aspiration for systematic nodal staging of lung cancer in patients with N0 disease by computed tomography and integrated positron emission tomography-computed tomography.对于经计算机断层扫描和正电子发射断层扫描-计算机断层扫描显示为N0期疾病的肺癌患者，采用支气管内超声引导下经支气管针吸活检进行系统性淋巴结分期。
Ann Am Thorac Soc. 2015 Mar;12(3):415-9. doi: 10.1513/AnnalsATS.201409-429OC.
9
Test performance of endobronchial ultrasound and transbronchial needle aspiration biopsy for mediastinal staging in patients with lung cancer: systematic review and meta-analysis.支气管内超声和经支气管针吸活检对肺癌纵隔分期的检测性能：系统评价和荟萃分析。
Thorax. 2009 Sep;64(9):757-62. doi: 10.1136/thx.2008.109868. Epub 2009 May 18.
10
Transbronchial and transesophageal fine-needle aspiration using an ultrasound bronchoscope in mediastinal staging of potentially operable lung cancer.超声支气管镜经支气管和经食管细针抽吸用于可手术肺癌的纵隔分期。
Chest. 2010 Oct;138(4):795-802. doi: 10.1378/chest.09-2100. Epub 2010 Mar 26.

引用本文的文献

1
A New Deep Learning-Based Method for Automated Identification of Thoracic Lymph Node Stations in Endobronchial Ultrasound (EBUS): A Proof-of-Concept Study.一种基于深度学习的支气管内超声（EBUS）中胸段淋巴结站自动识别新方法：概念验证研究。
J Imaging. 2025 Jan 5;11(1):10. doi: 10.3390/jimaging11010010.
2
Navigated ultrasound bronchoscopy with integrated positron emission tomography-A human feasibility study.导航超声支气管镜检查与正电子发射断层扫描集成——一项人体可行性研究。
PLoS One. 2024 Aug 30;19(8):e0305785. doi: 10.1371/journal.pone.0305785. eCollection 2024.
3
Automatic Segmentation of Mediastinal Lymph Nodes and Blood Vessels in Endobronchial Ultrasound (EBUS) Images Using Deep Learning.

本文引用的文献

1
CustusX: an open-source research platform for image-guided therapy.CustusX：一个用于图像引导治疗的开源研究平台。
Int J Comput Assist Radiol Surg. 2016 Apr;11(4):505-19. doi: 10.1007/s11548-015-1292-0. Epub 2015 Sep 26.
2
Versatile robotic probe calibration for position tracking in ultrasound imaging.用于超声成像中位置跟踪的多功能机器人探头校准
Phys Med Biol. 2015 May 7;60(9):3499-513. doi: 10.1088/0031-9155/60/9/3499. Epub 2015 Apr 9.
3
Navigated bronchoscopy: a technical review.导航支气管镜检查：技术综述。
利用深度学习自动分割支气管内超声（EBUS）图像中的纵隔淋巴结和血管
J Imaging. 2024 Aug 6;10(8):190. doi: 10.3390/jimaging10080190.
4
Multimodal Registration for Image-Guided EBUS Bronchoscopy.用于图像引导的超声支气管镜检查的多模态配准
J Imaging. 2022 Jul 8;8(7):189. doi: 10.3390/jimaging8070189.
5
A personalized image-guided intervention system for peripheral lung cancer on patient-specific respiratory motion model.基于患者特定呼吸运动模型的外周型肺癌个体化图像引导介入系统。
Int J Comput Assist Radiol Surg. 2022 Oct;17(10):1751-1764. doi: 10.1007/s11548-022-02676-2. Epub 2022 May 31.
6
Image-guided EBUS bronchoscopy system for lung-cancer staging.用于肺癌分期的图像引导超声支气管镜系统。
Inform Med Unlocked. 2021;25. doi: 10.1016/j.imu.2021.100665. Epub 2021 Jul 13.
7
Passive Magnetic-Flux-Concentrator Based Electromagnetic Targeting System for Endobronchoscopy.基于被动磁通量集中器的支气管内电磁靶向系统。
Sensors (Basel). 2019 Nov 21;19(23):5105. doi: 10.3390/s19235105.
8
Using the CustusX toolkit to create an image guided bronchoscopy application: Fraxinus.使用 CustusX 工具包创建图像引导支气管镜应用程序：Fraxinus。
PLoS One. 2019 Feb 8;14(2):e0211772. doi: 10.1371/journal.pone.0211772. eCollection 2019.
9
A software solution to dynamically reduce metallic distortions of electromagnetic tracking systems for image-guided surgery.一种软件解决方案，用于动态减少图像引导手术中电磁跟踪系统的金属变形。
Int J Comput Assist Radiol Surg. 2017 Sep;12(9):1621-1633. doi: 10.1007/s11548-017-1546-0. Epub 2017 Mar 3.
10
A multimodal image guiding system for Navigated Ultrasound Bronchoscopy (EBUS): A human feasibility study.一种用于导航超声支气管镜检查（EBUS）的多模态图像引导系统：一项人体可行性研究。
PLoS One. 2017 Feb 9;12(2):e0171841. doi: 10.1371/journal.pone.0171841. eCollection 2017.
J Bronchology Interv Pulmonol. 2014 Jul;21(3):242-64. doi: 10.1097/LBR.0000000000000064.
4
Automatic registration of CT images to patient during the initial phase of bronchoscopy: a clinical pilot study.支气管镜检查初始阶段CT图像与患者的自动配准：一项临床初步研究
Med Phys. 2014 Apr;41(4):041903. doi: 10.1118/1.4866884.
5
Revised ESTS guidelines for preoperative mediastinal lymph node staging for non-small-cell lung cancer.非小细胞肺癌术前纵隔淋巴结分期的修订版欧洲胸外科医师协会指南。
Eur J Cardiothorac Surg. 2014 May;45(5):787-98. doi: 10.1093/ejcts/ezu028. Epub 2014 Feb 26.
6
Beyond current guided bronchoscopy: a robust and real-time bronchoscopic ultrasound navigation system.超越当前的引导支气管镜检查：一种强大的实时支气管镜超声导航系统。
Med Image Comput Comput Assist Interv. 2013;16(Pt 1):388-95. doi: 10.1007/978-3-642-40811-3_49.
7
GPU accelerated segmentation and centerline extraction of tubular structures from medical images.基于GPU加速的医学图像中管状结构的分割与中心线提取
Int J Comput Assist Radiol Surg. 2014 Jul;9(4):561-75. doi: 10.1007/s11548-013-0956-x. Epub 2013 Nov 1.
8
Endobronchial ultrasound-guided transbronchial needle aspiration in the mediastinal staging of non-small cell lung cancer: a meta-analysis.经支气管超声引导针吸活检术在非小细胞肺癌纵隔分期中的应用：一项荟萃分析。
Ann Thorac Surg. 2013 Oct;96(4):1502-1507. doi: 10.1016/j.athoracsur.2013.05.016. Epub 2013 Aug 28.
9
Establishing the diagnosis of lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.肺癌的诊断：肺癌的诊断与管理，第 3 版：美国胸科医师学会循证临床实践指南。
Chest. 2013 May;143(5 Suppl):e142S-e165S. doi: 10.1378/chest.12-2353.
10
Electromagnetic navigational bronchoscopy: an effective and safe approach to diagnose peripheral lung lesions unreachable by conventional bronchoscopy in high-risk patients.电磁导航支气管镜检查：一种有效且安全的方法，用于诊断高危患者中传统支气管镜无法到达的周围型肺部病变。
J Bronchology Interv Pulmonol. 2011 Apr;18(2):133-7. doi: 10.1097/LBR.0b013e318216cee6.