Watanabe K, Hoshi H, Jinnouchi S, Yoshimura H, Nagamachi S
Rinsho Hoshasen. 1989 Mar;34(3):303-12.
At the first place, some experimental knowledges on the biodistribution of IMP were described for the understand of this agent. And on the basis of our clinical experience, the usefulness of cerebral perfusion imaging using SPECT and IMP was reviewed. The patients with possible ischemic cerebral diseases such as infarction, TIA and RIND are main candidates for this examination. Clinical significance of the so-called "redistribution" of IMP was discussed in detail. Dementia and epilepsy are considered to be the other indication. With improvement of the method, cerebral perfusion imaging may be accepted as essential test in the hospital dealing with the patient with neuropsychiatric deficits.
首先，为了了解IMP，描述了一些关于IMP生物分布的实验知识。并根据我们的临床经验，回顾了使用单光子发射计算机断层扫描（SPECT）和IMP进行脑灌注成像的实用性。患有可能的缺血性脑病如脑梗死、短暂性脑缺血发作（TIA）和可逆性缺血性神经功能缺损（RIND）的患者是这项检查的主要对象。详细讨论了IMP所谓“再分布”的临床意义。痴呆和癫痫被认为是其他适应症。随着方法的改进，脑灌注成像可能会被接受为医院处理神经精神功能缺损患者的必要检查。
