Minol Jan-Philipp, Akhyari Payam, Boeken Udo, Kamiya Hiroyuki, Weinreich Tobias, Sixt Stephan, Gramsch-Zabel Hildegard, Lichtenberg Artur
Department of Cardiovascular Surgery, University Hospital, Duesseldorf, Germany.
Department of Cardiovascular Surgery, University Hospital, Duesseldorf, Germany
Interact Cardiovasc Thorac Surg. 2016 Mar;22(3):287-90. doi: 10.1093/icvts/ivv323. Epub 2015 Nov 29.
According to demographic changes in the industrialized world, the average age of patients referred to cardiac surgery is increasing. These patients typically display numerous comorbidities, associated with increased perioperative risk. Therefore, the indication for a catheter-based therapy is progressively extended, including interventions on the mitral valve (MV). In this context, we evaluated a contemporary series of octogenarians undergoing minimally invasive MV surgery at our institution using right lateral minithoracotomy to elucidate the preoperative risk profile and the postoperative course in this particular cohort.
Between October 2009 and October 2014, 34 patients aged 80 years and older (82.5 ± 2.0) undergoing minimally invasive MV surgery were identified with a subgroup of 15 patients (44.1%) receiving concomitant surgery on the tricuspid valve (TV). We analysed the preoperative profile, perioperative course and functional outcome.
Preoperative comorbidities included insulin-dependent diabetes mellitus (17.6%), COPD (17.6%), active endocarditis (2.9%) and previous neurological events (2.9%). The mean left ventricular ejection fraction was 59.7 ± 6.9%. Mean European System for Cardiac Outcome Risk Evaluation II was 5.2 ± 5.3%. The repair rate of all treated MVs and TVs in isolated and combined procedures was 81.6% (73.5% for MV and 100.0% for TV surgery). Postoperatively, 4 patients (11.8%) required new-onset intermittent haemodialysis. Prolonged ventilation (>12 h) was necessary in 9 patients (26.5%). The 30-day mortality rate was 5.9%.
Minimally invasive right lateral MV surgery in octogenarians results in favourable outcomes. Therefore, MV surgery represents a valid option in this cohort, providing established and durable concepts of valve reconstruction.
根据工业化国家的人口结构变化,接受心脏手术的患者平均年龄在增加。这些患者通常伴有多种合并症,围手术期风险增加。因此,基于导管的治疗适应证正在逐步扩大,包括对二尖瓣(MV)的干预。在此背景下,我们评估了在我们机构接受右外侧小切口微创二尖瓣手术的一组当代八旬老人,以阐明该特定队列的术前风险概况和术后病程。
2009年10月至2014年10月期间,确定了34例年龄在80岁及以上(82.5±2.0岁)接受微创二尖瓣手术的患者,其中15例(44.1%)亚组患者同时接受了三尖瓣(TV)手术。我们分析了术前概况、围手术期病程和功能结局。
术前合并症包括胰岛素依赖型糖尿病(17.6%)、慢性阻塞性肺疾病(17.6%)、活动性心内膜炎(2.9%)和既往神经系统事件(2.9%)。平均左心室射血分数为59.7±6.9%。平均欧洲心脏手术风险评估系统II为5.2±5.3%。在单独和联合手术中,所有治疗的二尖瓣和三尖瓣的修复率为81.6%(二尖瓣手术为73.5%,三尖瓣手术为100.0%)。术后,4例患者(11.8%)需要开始新的间歇性血液透析。9例患者(26.5%)需要延长通气(>12小时)。30天死亡率为5.9%。
八旬老人行微创右外侧二尖瓣手术可获得良好结局。因此,二尖瓣手术是该队列中的一个有效选择,提供了成熟且持久的瓣膜重建概念。