Molvar Christopher, Lewandowski Robert
Section of Vascular and Interventional Radiology, Department of Radiology, Loyola University Medical Center, Maywood, Illinois.
Division of Interventional Oncology, Section of Interventional Radiology, Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Semin Intervent Radiol. 2015 Dec;32(4):388-97. doi: 10.1055/s-0035-1564704.
Hepatocellular carcinoma (HCC) is a lethal tumor, claiming over half a million lives per year. Treatment of HCC is commonly performed without curative intent, and palliative options dominate, including catheter-based therapies, namely, transarterial chemoembolization and yttrium-90 ((90)Y) radioembolization. This review will showcase the performance of (90)Y radioembolization for the treatment of HCC, focusing on recent seminal data and technical advances. In particular, novel radioembolization treatment concepts are discussed and compared with conventional HCC therapy.
肝细胞癌(HCC)是一种致命性肿瘤,每年导致超过50万人死亡。HCC的治疗通常不以治愈为目的,姑息治疗方法占主导,包括基于导管的治疗,即经动脉化疗栓塞术和钇-90(90Y)放射性栓塞术。本综述将展示90Y放射性栓塞术在治疗HCC方面的表现,重点关注近期的重要数据和技术进展。特别是,将讨论新型放射性栓塞治疗概念并与传统HCC治疗方法进行比较。