Orish Verner N, Ansong Joseph Y, Anagi Isaac B, Onyeabor Onyekachi S, Sanyaolu Adekunle O, Iriemenam Nnaemeka C
Effia-Nkwanta Regional Hospital Sekondi-Takoradi, Sekondi, Western Region, Ghana.
J Infect Dev Ctries. 2015 Nov 30;9(11):1257-63. doi: 10.3855/jidc.6316.
Children under five years of age are highly vulnerable to malaria infection and often face dire consequences such as severe malaria if they are not promptly and adequately treated with effective anti-malarial medications. We set out to evaluate malaria and associated co-morbidity among children admitted with febrile illness in Sekondi-Takoradi, Ghana.
This retrospective study focused on children admitted with fever over a three-year period at the pediatric unit of Effia-Nkwanta Regional Hospital. The children were identified, and the medical records of those who were successfully treated and discharged were searched, retrieved, and reviewed.
A total of 1,193 children were identified and selected for analysis. The mean duration of admission increased from 2.17 days in 2010 to 3.36 in 2012. Conversely, the mean age decreased from 3.85 years in 2010 to 2.74 in 2012. Overall, laboratory-confirmed malaria prevalence decreased; however, this decrease was only observed among children five years of age or younger, while malaria prevalence increased among children one year of age or younger. The proportion of children with severe malarial anemia significantly increased, while the proportion of those with mild malaria decreased significantly.
Despite the general decrease in malaria morbidity seen in this study, children younger than one year of age remain at increased risk of malaria morbidity. With an increase in malaria prevalence among children younger than one year of age over the three years of study, integrated and targeted control measures are highly needed for this age group.
五岁以下儿童极易感染疟疾，如果不及时用有效的抗疟药物进行充分治疗，往往会面临严重后果，如患重症疟疾。我们着手评估加纳塞康第 - 塔科拉迪因发热疾病入院儿童的疟疾及相关合并症情况。
这项回顾性研究聚焦于埃菲亚 - 恩夸塔地区医院儿科病房三年期间因发热入院的儿童。对这些儿童进行了识别，并对成功治疗出院的儿童病历进行了查找、检索和审查。
共识别并选取了1193名儿童进行分析。平均住院时间从2010年的2.17天增加到2012年的3.36天。相反，平均年龄从2010年的3.85岁降至2012年的2.74岁。总体而言，实验室确诊的疟疾患病率有所下降；然而，这种下降仅在五岁及以下儿童中观察到，而一岁及以下儿童的疟疾患病率有所上升。重症疟疾贫血儿童的比例显著增加，而轻度疟疾儿童的比例显著下降。
尽管本研究中疟疾发病率总体下降，但一岁以下儿童患疟疾的风险仍然增加。在三年的研究期间，一岁以下儿童的疟疾患病率上升，因此这个年龄组迫切需要综合和有针对性的控制措施。
