Alves Priscila Jesus Santos, Araujo Júnior Edward, Henriques Ana Ciléia Pinto Teixeira, Carvalho Francisco Herlânio Costa
a Department of Community Health, School of Medicine , Federal University of Ceará (UFC) , Fortaleza - CE , Brazil .
b Department of Obstetrics, Paulista School of Medicine , Federal University of São Paulo (EPM-UNIFESP) , São Paulo - SP , Brazil , and.
J Matern Fetal Neonatal Med. 2016 Oct;29(20):3351-7. doi: 10.3109/14767058.2015.1126577. Epub 2016 Jan 8.
To determine the effects of preterm birth and gender on subsequent cardiovascular risk factors among urban adolescents in a capital in the Brazilian northeast and to compare them with a group of adolescents term at birth.
In a retrospective double cohort, data of birth weight were extracted from hospital registers of children born in a same day of birth, between 1992 and 2002. We classified the preterm as a unique group born before 37 weeks of gestation. A total of 134 adolescents, aged 10-20 years were found and investigated. We measured anthropometric and clinical data, blood lipid profile and glucose after overnight fasting.
Preterm subjects had less years of scholar education, especially between females (p = 0.01). Preterm females also had lower height (p = 0.00) and waist-hip circumference ratio (p = 0.01). Preterm males had lower cesarean delivery (p = 0.05) and greater family history of cardiovascular disease (p = 0.05). Although the differences on clinical or laboratorial measurements were small and non-significant for cardiovascular risk factors, systolic blood pressure (SBP) and diastolic blood pressure (DBP) tended to be higher in preterm groups, especially for females (SBP = 4.1 mmHg and DBP = 1.6 mmHg, p = 0.12 and p = 0.38, respectively).
Premature did not increase cardiovascular risk adolescents in this sample. The lower association between premature and poor health outcomes among adolescents in a low average socioeconomic status population from a capital in the Brazilian northeast corroborates previous findings in other countries.
确定早产和性别对巴西东北部一个首府城市青少年后续心血管危险因素的影响，并将他们与一组足月出生的青少年进行比较。
在一项回顾性双队列研究中，从1992年至2002年同一天出生的儿童医院登记册中提取出生体重数据。我们将早产定义为妊娠37周前出生的单一组。共找到并调查了134名年龄在10 - 20岁的青少年。我们测量了人体测量和临床数据、空腹血脂谱和血糖。
早产受试者接受学校教育的年限较少，尤其是女性之间（p = 0.01）。早产女性的身高也较低（p = 0.00）和腰臀围比（p = 0.01）。早产男性剖宫产率较低（p = 0.05）且心血管疾病家族史较多（p = 0.05）。尽管临床或实验室测量方面的差异对于心血管危险因素而言较小且无统计学意义，但早产组的收缩压（SBP）和舒张压（DBP）往往较高，尤其是女性（SBP = 4.1 mmHg，DBP = 1.6 mmHg，p分别为0.12和0.38）。
在该样本中，早产并未增加青少年的心血管风险。来自巴西东北部一个首府城市、平均社会经济地位较低人群中的青少年早产与不良健康结局之间较低的关联证实了其他国家先前的研究结果。
