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经动脉化疗栓塞术后3D CACT辅助射频消融治疗肝细胞癌:早期经验

3D CACT-assisted Radiofrequency Ablation Following Transarterial Chemoembolization for Hepatocellular Carcinoma: Early Experience.

作者信息

Jiao De-Chao, Han Xin-Wei, Wu Gang, Ren Jian-Zhuang

机构信息

Department of Interventional Radiology, the First Affiliated Hospital of Zhengzhou University , Zhengzhou, China E-mail :

出版信息

Asian Pac J Cancer Prev. 2015;16(17):7897-903. doi: 10.7314/apjcp.2015.16.17.7897.

DOI:10.7314/apjcp.2015.16.17.7897
PMID:26625818
Abstract

BACKGROUND

To explored the value of 3D C-arm CT (CACT) guidance system in performing radiofrequency ablation (RFA) following transarterial chemoembolizationon (TACE) for hepatocellular carcinomas.

MATERIALS AND METHODS

RFA of hepatocellular carcinomas (HCC) were performed on 15 patients (21 lesions) with the assistance of CACT guidance system. Technical success, procedure time, complications and patient radiation exposure were investigated. The puncture performance level was evaluated on a five-point scale (5-1: excellent- poor). Complete ablation rate was evaluated after two months follow-up using enhanced CT scans.

RESULTS

The technical success rate of RFA procedure under CACT navigation system was 100%. Mean total procedure time was 24.24 ± 6.53 min, resulting in a mean effective exposure dose of 15.4 ± 5.1 mSv. The mean puncture performance level rated for CACT guided RFA procedure was 4.87 ± 0.35. Complete ablation (CA) was achieved in 20 (95.2%) of the treated 21 tumors after the first RFA session. None of patients developed intra-procedural complications.

CONCLUSIONS

3D CACT guidance system enables reliable and efficient needle positioning by providing real-time intraoperative guidance for performing RFA on HCCs.

摘要

背景

探讨三维C形臂CT(CACT)引导系统在肝细胞癌经动脉化疗栓塞术(TACE)后进行射频消融(RFA)中的应用价值。

材料与方法

在15例患者(21个病灶)中,借助CACT引导系统对肝细胞癌(HCC)进行射频消融。研究技术成功率、手术时间、并发症及患者辐射暴露情况。穿刺性能水平采用五点量表(5 - 1:优 - 差)进行评估。随访两个月后,使用增强CT扫描评估完全消融率。

结果

CACT导航系统下RFA手术的技术成功率为100%。平均总手术时间为24.24 ± 6.53分钟,平均有效暴露剂量为15.4 ± 5.1毫希沃特。CACT引导下RFA手术的平均穿刺性能水平评分为4.87 ± 0.35。首次RFA术后,21个治疗肿瘤中有20个(95.2%)实现了完全消融(CA)。所有患者均未发生术中并发症。

结论

三维CACT引导系统通过为肝癌射频消融提供实时术中引导,实现了可靠且高效的针定位。

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