Queen Alexandra Hospital, Portsmouth, United Kingdom.
Int J Surg. 2016 Jan;25:106-8. doi: 10.1016/j.ijsu.2015.11.041. Epub 2015 Nov 25.
To assess the effectiveness of rectal wash out in preventing local recurrence for patients who undergo anterior resection for recto-sigmoid cancer.
A best evidence topic was constructed according to a structured protocol. Medline 1948-2015 and EMBASE 1980 to 2015 using the OVID interface: ( Rectal) AND (Washout) AND (Anterior Resection). In addition, the reference lists of the relevant papers were searched.
Eight papers among the 17 relevant articles were identified as representing the best evidence including 3 prospective non-randomized studies, 1 retrospective non randomized study and 4 meta-analyses.
On the basis of current evidence, rectal washout does not stop local recurrence of cancer after anterior resection or left sided colonic resection, but it may reduce the rate of local recurrence. A randomised controlled trial to address this issue would formally answer this question.
评估直肠冲洗在预防接受直肠乙状结肠癌前切除术患者局部复发方面的有效性。
根据一个结构化的方案，构建了一个最佳证据主题。使用 OVID 界面，在 Medline 1948-2015 和 EMBASE 1980 至 2015 年期间，检索了（直肠）和（冲洗）和（前切除术）：此外，还检索了相关论文的参考文献列表。
在 17 篇相关文章中，有 8 篇文章被确定为最佳证据，包括 3 项前瞻性非随机研究、1 项回顾性非随机研究和 4 项荟萃分析。
根据目前的证据，直肠冲洗并不能阻止前切除术或左侧结肠切除术后癌症的局部复发，但它可能降低局部复发的发生率。进行一项随机对照试验来解决这个问题将正式回答这个问题。
