血浆前激肽释放酶的显色底物测定。附其生物合成部位说明。
Chromogenic substrate assay of plasma prekallikrein. With a note on its site of biosynthesis.
作者信息
Stormorken H, Baklund A, Gallimore M, Ritland S
出版信息
Haemostasis. 1978;7(2-3):69-75. doi: 10.1159/000214237.
PMID:26628
Abstract
A method for assaying plasma prekallikrein has been developed applying the chromogenic substrate Chromozym PK. Different variables have been investigated, and the final assay system was found to give a reproducible and reliable assay procedure. A normal value of 99.0 +/- 18% was found, the coefficient of variation being 7.9. Studies on material from patients with various liver diseases indicated that the main site of prekallikrein biosynthesis is the liver.
摘要
已开发出一种应用发色底物Chromozym PK检测血浆前激肽释放酶的方法。对不同变量进行了研究，发现最终的检测系统可提供可重复且可靠的检测程序。发现正常值为99.0 +/- 18%，变异系数为7.9。对各种肝病患者材料的研究表明，前激肽释放酶生物合成的主要部位是肝脏。
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