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曲安奈德气雾剂治疗一年对哮喘儿童生长模式影响的回顾性研究。

A retrospective review of the effects of one year of triamcinolone acetonide aerosol treatment on the growth patterns of asthmatic children.

作者信息

Brown D C, Savacool A M, Letizia C M

机构信息

Rorer Central Research, Horsham, Pennsylvania.

出版信息

Ann Allergy. 1989 Jul;63(1):47-51.

PMID:2662835
Abstract

Retrospective growth data were evaluated for 82 asthmatic children (59% dependent on oral corticosteroids) receiving triamcinolone acetonide aerosol for 1 year. Two-thirds of the steroid-dependent patients discontinued oral steroids. Triamcinolone acetonide did not adversely affect height or weight gain, although steroid-dependent asthmatics gained less weight than predicted, probably due to diminished fluid retention and appetite associated with decreased oral steroid doses and resolution of cushingoid features.

摘要

对82名接受曲安奈德气雾剂治疗1年的哮喘儿童(59%依赖口服皮质类固醇)的回顾性生长数据进行了评估。三分之二依赖类固醇的患者停用了口服类固醇。曲安奈德对身高或体重增加没有不利影响,尽管依赖类固醇的哮喘患者体重增加低于预期,这可能是由于口服类固醇剂量减少以及库欣样特征消退导致液体潴留和食欲下降。

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