针对疑似痛风进行的诊断性关节穿刺术是安全且耐受性良好的。
Diagnostic Arthrocentesis for Suspicion of Gout Is Safe and Well Tolerated.
作者信息
Taylor William J, Fransen Jaap, Dalbeth Nicola, Neogi Tuhina, Ralph Schumacher H, Brown Melanie, Louthrenoo Worawit, Vazquez-Mellado Janitzia, Eliseev Maxim, McCarthy Geraldine, Stamp Lisa K, Perez-Ruiz Fernando, Sivera Francisca, Ea Hang-Korng, Gerritsen Martijn, Scire Carlo A, Cavagna Lorenzo, Lin Chingtsai, Chou Yin-Yi, Tausche Anne-Kathrin, da Rocha Castelar-Pinheiro Geraldo, Janssen Matthijs, Chen Jiunn-Horng, Slot Ole, Cimmino Marco, Uhlig Till, Jansen Tim L
机构信息
From the University of Otago, Wellington; University of Auckland, Auckland; Department of Medicine, University of Otago Christchurch, Christchurch, New Zealand; Radboud University Medical Centre, Nijmegen; Amsterdam Rheumatology Immunology Center (ARC), Department of Rheumatology, Westfries Gasthuis, Hoorn; Rijnstate Hospital, Arnhem, the Netherlands; Boston University School of Medicine, Boston, Massachusetts; University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; Servicio de Reumatología, Hospital General de México, México City, México; Nasonova Research Institute of Rheumatology of Russia, Moscow, Russia; School of Medicine and Medical Science, University College Dublin; Mater Misericordiae University Hospital, Dublin, Ireland; Rheumatology Division, Hospital Universitario Cruces and BioCruces Health Research Institute, Vizcaya; Department Reumatologia, Hospital General Universitario de Elda, Alicante, Spain; Université Paris Diderot, Sorbonne Paris Cité, UFR de Médecine; Institut national de la santé et de la recherche médicale (INSERM), UMR 1132, Hôpital Lariboisière; Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Lariboisière, Service de Rhumatologie, Centre Viggo Petersen, Pôle Appareil Locomoteur, Paris, France; Epidemiology Unit, Italian Society for Rheumatology (SIR), Milan; Division of Rheumatology, University and IRCCS Policlinico S. Matteo Foundation, Pavia; Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genoa, Genoa, Italy; Division of Rheumatology and Immunology, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation; Taichung Veterans' General Hospital; School of Medicine, China Medical University; Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan; Division of Rheumatology, Department of In
出版信息
J Rheumatol. 2016 Jan;43(1):150-3. doi: 10.3899/jrheum.150684. Epub 2015 Dec 1.
OBJECTIVE
To determine the frequency of adverse events of diagnostic arthrocentesis in patients with possible gout.
METHODS
Consecutive patients underwent arthrocentesis and were evaluated at 6 weeks to determine adverse events. The 95% CI were obtained by bootstrapping.
RESULTS
Arthrocentesis was performed in 910 patients, and 887 (97.5%) were evaluated for adverse events. Any adverse event was observed in 12 participants (1.4%, 95% CI 0.6-2.1). There was 1 case (0.1%, 95% CI 0-0.34) of septic arthritis.
CONCLUSIONS
Diagnostic arthrocentesis is associated with a low frequency of adverse events. Septic arthritis rarely occurs.
目的
确定疑似痛风患者诊断性关节穿刺术不良事件的发生率。
方法
连续纳入接受关节穿刺术的患者，并在6周时进行评估以确定不良事件。通过自抽样法获得95%置信区间。
结果
910例患者接受了关节穿刺术，其中887例（97.5%）接受了不良事件评估。12名参与者（1.4%，95%置信区间0.6 - 2.1）出现任何不良事件。有1例脓毒性关节炎（0.1%，95%置信区间0 - 0.34）。
结论
诊断性关节穿刺术不良事件发生率较低。脓毒性关节炎很少发生。
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