Nair Kavitha, George Thomas, El Beltagi Ahmed
Department of Radiology, Kuwait Cancer Control Center, Kuwait.
Department of Radiation Oncology, Kuwait Cancer Control Center, Kuwait.
J Radiol Case Rep. 2015 Aug 31;9(8):8-15. doi: 10.3941/jrcr.v9i8.2185. eCollection 2015 Aug.
Malignant trigeminal neuralgia due to perineural spread along the branches of the trigeminal nerve, is known to commonly occur secondary to squamous cell carcinomas, lymphomas and adenoid cystic carcinomas in the head and neck region. Rarely metastases to the trigeminal nerve have been reported in breast cancer, prostate cancer and colon cancer. To the best of our knowledge trigeminal neuropathy due to skull base metastases and perineural spread along the maxillary (V2) and mandibular (V3) branches of the trigeminal nerve, secondary to colon cancer, has not been previously reported. The diagnosis in our index case was made on magnetic resonance imaging, and patient was treated accordingly by fractionated stereotactic radiotherapy, with subsequent relief of her pain.
恶性三叉神经痛因神经周围沿三叉神经分支扩散而引起，常见于头颈部区域的鳞状细胞癌、淋巴瘤和腺样囊性癌继发。乳腺癌、前列腺癌和结肠癌转移至三叉神经的情况罕见报道。据我们所知，结肠癌继发颅底转移及神经周围沿三叉神经上颌支（V2）和下颌支（V3）扩散导致的三叉神经病变此前未见报道。我们索引病例的诊断通过磁共振成像做出，患者接受了分次立体定向放射治疗，疼痛随后缓解。
