1 Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea ; 2 Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Transl Lung Cancer Res. 2015 Oct;4(5):656-9. doi: 10.3978/j.issn.2218-6751.2015.04.05.
Ground-glass opacity nodules (GGNs) in the lung attract clinical attention owing to their increasing incidence, unique natural course, and association with lung adenocarcinoma. A long and indolent course of a GGN makes it difficult to manage. Current extensive clinical, radiological, pathological, and genetic studies on GGNs have shed light on their pathogenesis and allowed development of a reliable strategy of management. The present editorial provides answers to clinical questions related to GGNs, such as the natural course, follow-up, prediction of growth, and resection techniques. Finally, I discuss the etiology of GGNs, which has not been fully elucidated so far.
肺部磨玻璃密度结节（GGNs）由于其发病率的增加、独特的自然病程以及与肺腺癌的关系而引起临床关注。GGN 的漫长和惰性病程使其难以管理。目前对 GGN 的广泛临床、放射学、病理学和遗传学研究揭示了其发病机制，并为可靠的管理策略的制定提供了依据。本社论就 GGN 相关的临床问题提供了答案，例如自然病程、随访、生长预测和切除技术。最后，我还讨论了 GGN 的病因，目前尚未完全阐明。
