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从一名尿路感染患者分离出的粘质沙雷氏菌菌株RM66262的全基因组序列草图

Draft Whole-Genome Sequence of Serratia marcescens Strain RM66262, Isolated from a Patient with a Urinary Tract Infection.

作者信息

Bruna Roberto E, Revale Santiago, García Véscovi Eleonora, Mariscotti Javier F

机构信息

Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET), Departamento de Microbiología, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Argentina.

Instituto de Agrobiotecnología Rosario (INDEAR)-CONICET, Rosario, Argentina.

出版信息

Genome Announc. 2015 Dec 3;3(6):e01423-15. doi: 10.1128/genomeA.01423-15.

DOI:10.1128/genomeA.01423-15
PMID:26634764
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4669405/
Abstract

Serratia marcescens strains are ubiquitous bacteria isolated from environmental niches and also constitute emergent nosocomial opportunistic pathogens. Here, we report on the draft genome sequence of S. marcescens strain RM66262, which was isolated from a patient with urinary tract infection in the Bacteriology Service of the Rosario National University, Rosario, Argentina.

摘要

粘质沙雷氏菌菌株是从环境生态位中分离出的普遍存在的细菌，也是新出现的医院机会致病菌。在此，我们报告了粘质沙雷氏菌菌株RM66262的基因组草图序列，该菌株是从阿根廷罗萨里奥国立大学细菌学服务部一名尿路感染患者中分离出来的。

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本文引用的文献

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A5-miseq: an updated pipeline to assemble microbial genomes from Illumina MiSeq data.A5-miseq：一种用于从Illumina MiSeq数据组装微生物基因组的更新流程。
Bioinformatics. 2015 Feb 15;31(4):587-9. doi: 10.1093/bioinformatics/btu661. Epub 2014 Oct 22.
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Serratia marcescens ShlA pore-forming toxin is responsible for early induction of autophagy in host cells and is transcriptionally regulated by RcsB.粘质沙雷氏菌 ShlA 孔形成毒素负责诱导宿主细胞早期自噬，其转录受到 RcsB 的调控。
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An integrated pipeline for de novo assembly of microbial genomes.用于从头组装微生物基因组的集成管道。
PLoS One. 2012;7(9):e42304. doi: 10.1371/journal.pone.0042304. Epub 2012 Sep 13.
4
Biogenesis of outer membrane vesicles in Serratia marcescens is thermoregulated and can be induced by activation of the Rcs phosphorelay system.粘质沙雷氏菌外膜囊泡的生物发生受温度调控，并可通过 Rcs 磷酸传递系统的激活而诱导。
J Bacteriol. 2012 Jun;194(12):3241-9. doi: 10.1128/JB.00016-12. Epub 2012 Apr 6.
5
The PhoP/PhoQ system and its role in Serratia marcescens pathogenesis.磷酸烯醇式丙酮酸/磷酸烯醇丙酮酸受体系统及其在粘质沙雷氏菌发病机制中的作用。
J Bacteriol. 2012 Jun;194(11):2949-61. doi: 10.1128/JB.06820-11. Epub 2012 Mar 30.
6
Serratia infections: from military experiments to current practice.沙雷氏菌感染：从军事实验到当前实践。
Clin Microbiol Rev. 2011 Oct;24(4):755-91. doi: 10.1128/CMR.00017-11.
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Serratia marcescens is able to survive and proliferate in autophagic-like vacuoles inside non-phagocytic cells.黏质沙雷氏菌能够在非吞噬细胞的自噬样小泡中存活和增殖。
PLoS One. 2011;6(8):e24054. doi: 10.1371/journal.pone.0024054. Epub 2011 Aug 25.
8
The Rcs signal transduction pathway is triggered by enterobacterial common antigen structure alterations in Serratia marcescens.Rcs 信号转导途径是由粘质沙雷氏菌中肠杆菌共同抗原结构改变触发的。
J Bacteriol. 2011 Jan;193(1):63-74. doi: 10.1128/JB.00839-10. Epub 2010 Oct 22.
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The RAST Server: rapid annotations using subsystems technology.RAST服务器：使用子系统技术进行快速注释。
BMC Genomics. 2008 Feb 8;9:75. doi: 10.1186/1471-2164-9-75.
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Enterobacterial common antigen integrity is a checkpoint for flagellar biogenesis in Serratia marcescens.肠杆菌共同抗原完整性是粘质沙雷氏菌鞭毛生物合成的一个检查点。
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