Li Hongjun, Bai Gang, Zhang Xinyu, Shi Bingbing, Liu Defeng, Jiang Hui, Ji Zhigang, Davis Matthew R, Zhu Ziwen, Fang Yujiang
1 Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China.
2 Peking University Third Hospital, Beijing, China.
Am J Mens Health. 2017 May;11(3):525-530. doi: 10.1177/1557988315620467. Epub 2015 Dec 3.
To investigate the effects of two different dosages of sildenafil on patients with erectile dysfunction (ED), a total of 3,674 patients with ED were recruited to answer questionnaires designed specifically for this study. There were 977 patients in the 50 mg group and there were 2,697 patients in the 100 mg group. Both 50 mg and 100 mg of sildenafil therapy increased the ED patients' average monthly frequency of sexual intercourse, improved erectile function state in self-assessment, and elevated sexual satisfaction and enjoyment. Despite a higher rate of concomitant diseases, patients in the higher dosage of sildenafil group had a better outcome in the average monthly frequency of sexual intercourse and sexual enjoyment compared with those in the lower dosage. Such a study might be helpful for health care providers to choose sildenafil dosage for patients with ED.
为研究两种不同剂量西地那非对勃起功能障碍（ED）患者的影响，共招募了3674例ED患者来回答专门为此研究设计的问卷。50毫克组有977例患者，100毫克组有2697例患者。50毫克和100毫克的西地那非治疗均增加了ED患者的平均每月性交频率，改善了自我评估中的勃起功能状态，并提高了性满意度和性快感。尽管合并疾病发生率较高，但与低剂量组相比，高剂量西地那非组患者在平均每月性交频率和性快感方面的结果更好。这样的研究可能有助于医疗保健提供者为ED患者选择西地那非剂量。
