Zanella Rafaela Koehler, Valente Denis Souto, Doncatto Leo Francisco, Rossi Daniele Dos Santos, Lerias Aline Grimaldi, Padoin Alexandre Vontobel
Mãe de Deus Health System, Rua Soledade 569, 90470-340 Porto Alegre, RS, Brazil.
Graduate Program in Medicine and Health Sciences, School of Medicine, PUCRS (FAMED), Avenida Ipiranga 6681, 90619-900 Porto Alegre, RS, Brazil.
Dermatol Res Pract. 2015;2015:640482. doi: 10.1155/2015/640482. Epub 2015 Nov 9.
Vitamin D (VD) plays a role in the skin regulation. Striae Distensae (SD) are manifestations of epidermal atrophy that occurs after tissue tearing due to overstretching or rapid growth. The objective of this study was to investigate the relation between serum VD and occurrence of SD in women who had undergone mammaplasty with silicone implants. A case-referent study was conducted. The blood values of 25-hydroxyvitamin D (25OHD) were measured before the surgery. For each patient postoperatively diagnosed with SD, four other participants submitted to the same surgery, without the development of SD, were enrolled as the healthy controls. 67 women with SD after the surgery entered the study. 268 formed the control group. In the serum of healthy controls 25OHD mean was 27 ng/mL, and SD cases presented 20 ng/mL (P = 0.01). Scarce values of VD have been observed in 56.71% of the cases presenting SD and in 39.91% without SD (P = 0.002). Chance of having VD values lower than 20 ng/mL amongst cases with SD is 2.38 (P = 0.0001). Lower serum levels of VD are linked to a higher occurrence of SD.
维生素D（VD）在皮肤调节中发挥作用。膨胀纹（SD）是由于过度拉伸或快速生长导致组织撕裂后发生的表皮萎缩表现。本研究的目的是调查接受硅胶假体隆胸手术的女性血清VD与SD发生之间的关系。进行了一项病例对照研究。在手术前测量25-羟基维生素D（25OHD）的血液值。对于术后诊断为SD的每位患者，另外四名接受相同手术但未发生SD的参与者被纳入作为健康对照。67名术后出现SD的女性进入研究。268名组成对照组。健康对照组血清中25OHD的平均值为27 ng/mL，而SD病例为20 ng/mL（P = 0.01）。在出现SD的病例中，56.71%的病例VD值较低，在未出现SD的病例中为39.91%（P = 0.002）。SD病例中VD值低于20 ng/mL的几率为2.38（P = 0.0001）。较低的血清VD水平与较高的SD发生率相关。
