公共卫生领域的基因组学：美国疾病控制与预防中心（CDC）公共卫生基因组学办公室的观点
Genomics in Public Health: Perspective from the Office of Public Health Genomics at the Centers for Disease Control and Prevention (CDC).
作者信息
Green Ridgely Fisk, Dotson W David, Bowen Scott, Kolor Katherine, Khoury Muin J
机构信息
Carter Consulting, Inc. and Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
出版信息
Healthcare (Basel). 2015;3(3):830-7. doi: 10.3390/healthcare3030830. Epub 2015 Sep 15.
The national effort to use genomic knowledge to save lives is gaining momentum, as illustrated by the inclusion of genomics in key public health initiatives, including Healthy People 2020, and the recent launch of the precision medicine initiative. The Office of Public Health Genomics (OPHG) at the Centers for Disease Control and Prevention (CDC) partners with state public health departments and others to advance the translation of genome-based discoveries into disease prevention and population health. To do this, OPHG has adopted an "identify, inform, and integrate" model: identify evidence-based genomic applications ready for implementation, inform stakeholders about these applications, and integrate these applications into public health at the local, state, and national level. This paper addresses current and future work at OPHG for integrating genomics into public health programs.
利用基因组知识拯救生命的全国性努力正在加速推进，这体现在基因组学被纳入关键的公共卫生倡议中，包括《健康人民2020》，以及最近启动的精准医学倡议。疾病控制与预防中心（CDC）的公共卫生基因组学办公室（OPHG）与州公共卫生部门及其他机构合作，推动将基于基因组的发现转化为疾病预防和群体健康。为此，OPHG采用了“识别、告知与整合”模式：识别准备好实施的基于证据的基因组应用，向利益相关者通报这些应用，并将这些应用整合到地方、州和国家层面的公共卫生工作中。本文阐述了OPHG目前及未来将基因组学整合到公共卫生项目中的工作。
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