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儿童中央型肿瘤的肝中叶切除术

Mesohepatectomy for Centrally Located Tumors in Children.

作者信息

Amesty Maria Virginia, Chocarro Gloria, Vilanova Sánchez Alejandra, Nuñez Cerezo Vanesa, de la Torre C A, Encinas Jose Luis, Gamez Arance Manuel, Hernández Francisco, Lopez Santamaria Manuel

机构信息

Department of Pediatric Surgery, Hospital Universitario La Paz, Madrid, Madrid, Spain.

出版信息

Eur J Pediatr Surg. 2016 Feb;26(1):128-32. doi: 10.1055/s-0035-1568995. Epub 2015 Dec 4.

Abstract

INTRODUCTION

Central hepatectomy or mesohepatectomy (MH) is a complex surgical technique rarely used in children. It is indicated in central tumors to preserve functioning liver mass avoiding an extended right hepatectomy. The purpose of this article is to analyze our experience with this technique.

METHODS

We reviewed five patients who underwent MH in the period from 2008 to 2014. Diagnoses were hepatoblastoma PRETEXT III (two cases), hepatic embryonal sarcoma (one case), focal nodular hyperplasia (one case), and vascular tumor with rapid growth in a newborn causing an acute liver failure, compartment syndrome, and multiple organ failure (one case). In all cases, the tumor was centrally located, including the segment IVb, with large displacement of the hepatic pedicle in two cases.

RESULTS

MH was standard in three cases and under total vascular exclusion in two cases. All children are alive with a mean follow-up of 38 (6-70) months. None of the children required reoperation because of bleeding. One child developed a biliary fistula in the cutting area that closed spontaneously. The newborn with the vascular tumor required the placement of a Gore-Tex patch (W. L. Gore & Associates, Inc, Flagstaff, Arizona, United States) to relieve the compartment syndrome. He subsequently underwent partial embolization of the tumor and MH under vascular exclusion.

CONCLUSIONS

In selected patients, MH is an alternative to trisegmentectomy and should be available in advanced pediatric hepatobiliary units.

摘要

引言

中央肝切除术或肝中叶切除术(MH)是一种复杂的外科技术,在儿童中很少使用。它适用于中央型肿瘤,以保留有功能的肝组织,避免进行扩大的右肝切除术。本文的目的是分析我们在这项技术方面的经验。

方法

我们回顾了2008年至2014年期间接受MH手术的5例患者。诊断包括肝母细胞瘤PRETEXT III期(2例)、肝胚胎性肉瘤(1例)、局灶性结节性增生(1例),以及1例新生儿期快速生长的血管性肿瘤,导致急性肝衰竭、骨筋膜室综合征和多器官功能衰竭。所有病例中,肿瘤均位于中央,包括IVb段,2例肝蒂有较大移位。

结果

3例采用标准的MH手术,2例采用全肝血流阻断。所有患儿均存活,平均随访38(6 - 70)个月。没有患儿因出血需要再次手术。1例患儿在手术切缘出现胆瘘,自行愈合。患有血管性肿瘤 的新生儿需要放置一块戈尔特斯补片(美国亚利桑那州弗拉格斯塔夫市的W. L. 戈尔公司)以缓解骨筋膜室综合征。随后,他在血流阻断下接受了肿瘤部分栓塞和MH手术。

结论

对于特定患者,MH是三段肝切除术的一种替代方法,先进的小儿肝胆外科单位应具备此项技术。

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