Gautier E, Gallusser A, Despland P A
Institut de Microbiologie, Centre Hospitalier Universitaire Vaudois, Lausanne.
Helv Paediatr Acta. 1989 Jun;43(5-6):521-30.
The authors describe a case of botulism in a 3-month-old infant infected with Clostridium botulinum type A. Symptomatology developed within four days, persisted for two weeks, then regressed. Symptoms were paresis of face muscles, hyporeactive pupils, loss of succion and deglutition, axial hypotonia, weakness of peripheral muscles, lability of the autonomic nervous system with acute episodes of bradycardia and constipation. Anomalies of the electroen-cephalogram and of the auditory evoked responses suggest that the toxin penetrated the central nervous system. Treatment was symptomatic, without need for assisted ventilation. It was not possible to detect the source of infection.
作者描述了一例3个月大感染A型肉毒杆菌的婴儿肉毒中毒病例。症状在4天内出现，持续了两周，然后消退。症状包括面部肌肉麻痹、瞳孔反应迟钝、吸吮和吞咽功能丧失、轴向肌张力减退、外周肌肉无力、自主神经系统不稳定伴心动过缓和便秘急性发作。脑电图和听觉诱发电位异常表明毒素已侵入中枢神经系统。治疗以对症治疗为主，无需辅助通气。无法检测到感染源。
