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中心性浆液性脉络膜视网膜病变与风湿性疾病中的全身用糖皮质激素:三例报告

Central serous chorioretinopathy and systemic corticosteroids in rheumatic diseases: report of three cases.

作者信息

Valls Pascual Elia, Martínez-Costa Lucía, Santander Fernando

机构信息

Rheumatology Department, Hospital Universitari Doctor Peset, Juan de Garay, 21, 46017, Valencia, Spain.

Ophthalmology Department, Hospital Universitari Doctor Peset, Valencia, Spain.

出版信息

BMC Musculoskelet Disord. 2015 Dec 5;16:378. doi: 10.1186/s12891-015-0843-4.

Abstract

BACKGROUND

Central serous chorioretinopathy is a disorder often related to systemic corticosteroids, drugs commonly used in rheumatologists' clinical practice. Central serous chorioretinopathy prognosis is generally good but in some cases, it may lead to substantial loss of vision resulting in an important functional limitation for patients. It is very important to distinguish this pathology from other diseases involving retinal detachment. When central serous chorioretinopathy and uveitis coexist, it is mandatory to distinguish serous retinal detachment from a uveitis worsening, as the respective treatments can be radically different.

CASE PRESENTATION

We describe three cases of central serous chorioretinopathy in patients taking systemic corticosteroids due to rheumatological diseases (ankylosing spondylitis, systemic lupus erythematosus and Behçet's disease). They were diagnosed and managed at our Multidisciplinary (Rheumatology-Ophthalmology) Uveitis Clinic. All three cases improved after corticosteroids dose tapering.

CONCLUSION

Central serous chorioretinopathy must be kept in mind by rheumatologists as it is related to systemic corticosteroids.

摘要

背景

中心性浆液性脉络膜视网膜病变是一种常与全身用糖皮质激素相关的疾病,这类药物常用于风湿病学家的临床实践中。中心性浆液性脉络膜视网膜病变的预后通常良好,但在某些情况下,可能导致严重的视力丧失,给患者带来重要的功能限制。将这种病变与其他涉及视网膜脱离的疾病区分开来非常重要。当中心性浆液性脉络膜视网膜病变与葡萄膜炎并存时,必须区分浆液性视网膜脱离与葡萄膜炎的恶化,因为各自的治疗方法可能截然不同。

病例介绍

我们描述了3例因风湿性疾病(强直性脊柱炎、系统性红斑狼疮和白塞病)而服用全身用糖皮质激素的患者发生中心性浆液性脉络膜视网膜病变的病例。这些病例在我们的多学科(风湿病学 - 眼科)葡萄膜炎诊所得到诊断和治疗。所有3例在糖皮质激素减量后病情均有改善。

结论

风湿病学家必须牢记中心性浆液性脉络膜视网膜病变,因为它与全身用糖皮质激素有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a55/4670548/f1c736936611/12891_2015_843_Fig1_HTML.jpg

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