Kirk M D
Boston University, Department of Biology, Massachusetts 02215.
J Neurobiol. 1989 Jul;20(5):497-512. doi: 10.1002/neu.480200516.
Central pattern generator (CPG) circuits control cyclic motor output underlying rhythmic behaviors. Although there have been extensive behavioral and cellular studies of food-induced feeding arousal as well as satiation in Aplysia, very little is known about the neuronal circuits controlling rhythmic consummatory feeding behavior. However, recent studies have identified premotor neurons that initiate and maintain buccal motor programs underlying ingestion and egestion in Aplysia. Other newly identified neurons receive synaptic input from feeding CPGs and in turn synapse with and control the output of buccal motor neurons. Some of these neurons and their effects within the buccal system are modulated by endogenous neuropeptides. With this information we can begin to understand how neuronal networks control buccal motor output and how their activity is modulated to produce flexibility in observed feeding behavior.
中枢模式发生器（CPG）电路控制着节律性行为背后的周期性运动输出。尽管对海兔中食物诱导的进食觉醒以及饱腹感已经进行了广泛的行为和细胞研究，但对于控制节律性进食行为的神经回路却知之甚少。然而，最近的研究已经确定了启动和维持海兔摄食和排泄所依据的口腔运动程序的运动前神经元。其他新发现的神经元从进食CPG接收突触输入，进而与口腔运动神经元形成突触并控制其输出。这些神经元中的一些及其在口腔系统内的作用受到内源性神经肽的调节。有了这些信息，我们就可以开始了解神经网络如何控制口腔运动输出，以及它们的活动如何被调节以在观察到的进食行为中产生灵活性。
