Pathologic Criteria to Estimate the State of the Liver in Potential Donors.
作者信息
Shaimardanova Caliya, Fedotovskikh Galina, Savchuk Aleksandr, Doszhan Ainura, Smagulova Aigerim, Gaipov Abduzhappar
机构信息
From the Department of Pathology, JSC National Scientific Medical Research Center, Astana, Kazakhstan.
出版信息
Exp Clin Transplant. 2015 Nov;13 Suppl 3:33-5. doi: 10.6002/ect.tdtd2015.O23.
OBJECTIVES
The pathologic evaluation of the liver is one of the most important issues in liver transplants. We evaluated the histopathological condition of livers in potential donors.
MATERIALS AND METHODS
After liver biopsy, 37 potential donor livers were histologically studied. Liver tissue was stained by hematoxylin and eosin as well as Masson Trichrome.
RESULTS
The results of the study showed the morphologic criteria used to estimate the state of the liver in potential donors is not only steatosis and fibrosis, but other important histologic criteria, such as proteinosis, necrosis of hepatocytes, endotheliitis of central veins, inflammatory infiltration, endarteritis in portal tracts and phlebitis in portal tracts, proliferation of the bile ducts, and cholestasis.
CONCLUSIONS
Results of the study showed that the morphologic criteria to estimate the state of the liver in potential donors includes not only steatosis and fibrosis, but other important histologic criteria as well.
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