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低危前列腺癌根治性前列腺切除术后延迟肾移植

Delaying Renal Transplant after Radical Prostatectomy for Low-Risk Prostate Cancer.

作者信息

Özçelik Ümit, Bircan Hüseyin Yüce, Karakayalı Feza, Moray Gökhan, Demirağ Alp

机构信息

From the Department of General Surgery, Baskent University School of Medicine, Istanbul, Turkey.

出版信息

Exp Clin Transplant. 2015 Nov;13 Suppl 3:74-6. doi: 10.6002/ect.tdtd2015.P28.

DOI:10.6002/ect.tdtd2015.P28
PMID:26640918
Abstract

To minimize the recurrence of a previously treated neoplasm in organ recipients, a period of 2 to 5 years without recurrence is advocated for most malignancies. However, prostate cancer is different because of its biological properties, diagnosis, and treatment. Most prostate cancers are detected at a low stage and demonstrate slow growth after detection. Definitive treatment with radical prostatectomy affords excellent results. Renal transplant candidates with early-stage prostate cancer have a higher risk of dying on dialysis than dying from prostate cancer; therefore, renal transplant candidates with organ-confined prostate cancer should be immediately considered for transplant.

摘要

为了尽量减少器官移植受者中既往治疗过的肿瘤的复发,对于大多数恶性肿瘤,提倡有2至5年无复发的时期。然而,前列腺癌因其生物学特性、诊断和治疗而有所不同。大多数前列腺癌在早期被检测到,并且在检测后显示生长缓慢。根治性前列腺切除术的确定性治疗效果极佳。患有早期前列腺癌的肾移植候选者在透析时死亡的风险高于死于前列腺癌的风险;因此,患有器官局限性前列腺癌的肾移植候选者应立即考虑进行移植。

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