Ersoy Ozgur, Gultekin Bahadir, Ozkan Murat, Akkaya Ilknur, Umaroglu Sevi, Sezgin Atilla
From the Department of Cardiovascular Surgery, Baskent University Faculty of Medicine, Ankara, Turkey 06490.
Exp Clin Transplant. 2015 Nov;13 Suppl 3:137-9. doi: 10.6002/ect.tdtd2015.P73.
Red blood cell distribution width is a measure of the variability in the size of circulating erythrocytes, which is calculated by automated blood cell counters as part of a routine blood cell count analysis. Our aim was to examine whether continuous flow left ventricular assist devices affected red blood cell distribution width.
Our study included 16 of 24 patients who received a HeartWare HVAD Pump (HeartWare Inc, Framingham, MA, USA) implant (continuous flow left ventricular assist device) between April 2012 and February 2015 at our institution. The mean age of the patients was 46.6 years. We compared patient erythrocyte, leucocyte, and platelet counts, hemoglobin and hematocrit levels, mean corpuscular volume, and red blood cell distribution width values before and 6 months after implant.
Hemoglobin level (P = .008), hematocrit level (P = .027), and mean corpuscular volume (P = .003) were significantly decreased; however, we observed no significant change in red blood cell distribution width.
Although we did not find significant results in our group of patients with left ventricular assist device implant, a larger group of patients may show more significant results, and an increase in red blood cell distribution width can be used as an indicator of a negative prognosis in these patients.
红细胞分布宽度是衡量循环红细胞大小变异性的指标，由自动血细胞计数器在常规血细胞计数分析时计算得出。我们的目的是研究持续血流左心室辅助装置是否会影响红细胞分布宽度。
我们的研究纳入了2012年4月至2015年2月期间在我院接受HeartWare HVAD泵（美国马萨诸塞州弗雷明汉市HeartWare公司）植入术（持续血流左心室辅助装置）的24例患者中的16例。患者的平均年龄为46.6岁。我们比较了患者植入前及植入后6个月的红细胞、白细胞和血小板计数、血红蛋白和血细胞比容水平、平均红细胞体积以及红细胞分布宽度值。
血红蛋白水平（P = 0.008）、血细胞比容水平（P = 0.027）和平均红细胞体积（P = 0.003）显著降低；然而，我们观察到红细胞分布宽度没有显著变化。
尽管在我们植入左心室辅助装置的患者组中未发现显著结果，但更大规模的患者组可能会显示出更显著的结果，红细胞分布宽度增加可作为这些患者预后不良的指标。
