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肯尼亚尼扬扎省农村社区新型抗菌毛巾对2岁以下儿童健康影响的整群随机对照评估。

A Cluster Randomized Controlled Evaluation of the Health Impact of a Novel Antimicrobial Hand Towel on the Health of Children Under 2 Years Old in Rural Communities in Nyanza Province, Kenya.

作者信息

Slayton Rachel B, Murphy Jennifer L, Morris Jamae, Faith Sitnah Hamidah, Oremo Jared, Odhiambo Aloyce, Ayers Tracy, Feinman Shawna J, Brown Allison C, Quick Robert E

机构信息

Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia; Safe Water and AIDS Project, Kisumu, Kenya

Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia; Safe Water and AIDS Project, Kisumu, Kenya.

出版信息

Am J Trop Med Hyg. 2016 Feb;94(2):437-44. doi: 10.4269/ajtmh.14-0566. Epub 2015 Dec 7.

Abstract

To assess the health impact of reusable, antimicrobial hand towels, we conducted a cluster randomized, yearlong field trial. At baseline, we surveyed mothers, and gave four towels plus hygiene education to intervention households and education alone to controls. At biweekly home visits, we asked about infections in children < 2 years old and tested post-handwashing hand rinse samples of 20% of mothers for Escherichia coli. At study's conclusion, we tested 50% of towels for E. coli. Baseline characteristics between 188 intervention and 181 control households were similar. Intervention and control children had similar rates of diarrhea (1.47 versus 1.48, P = 0.99), respiratory infections (1.38 versus 1.48, P = 0.92), skin infections (1.76 versus 1.79, P = 0.81), and subjective fever (2.62 versus 3.40, P = 0.04) per 100 person-visits. Post-handwashing hand contamination was similar; 67% of towels exhibited E. coli contamination. Antimicrobial hand towels became contaminated over time, did not improve hand hygiene, or prevent diarrhea, respiratory infections, or skin infections.

摘要

为评估可重复使用的抗菌手巾对健康的影响,我们开展了一项为期一年的整群随机现场试验。在基线期,我们对母亲们进行了调查,并向干预家庭发放了四条手巾并提供卫生教育,向对照家庭仅提供教育。在每两周一次的家访中,我们询问了2岁以下儿童的感染情况,并对20%的母亲洗手后的冲洗样本进行了大肠杆菌检测。在研究结束时,我们对50%的手巾进行了大肠杆菌检测。188个干预家庭和181个对照家庭的基线特征相似。干预组和对照组儿童每100人次的腹泻发生率(分别为1.47和1.48,P = 0.99)、呼吸道感染发生率(分别为1.38和1.48,P = 0.92)、皮肤感染发生率(分别为1.76和1.79,P = 0.81)以及主观发热发生率(分别为2.62和3.40,P = 0.04)相似。洗手后手部污染情况相似;67%的手巾检测出大肠杆菌污染。抗菌手巾随着时间推移会被污染,并未改善手部卫生状况,也未预防腹泻、呼吸道感染或皮肤感染。

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