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肝移植活体供者围手术期钙、镁和磷水平

Perioperative Calcium, Magnesium, and Phosphorus Levels in Live Donors For Liver Transplant.

作者信息

Mahmoud Ahmed A A, El-Shaarawy Ahmed Mostafa, Mansour Mohamed Ahmed, Abdelhaq Mohamed Mohamed, Maher Mohamed Ahmed, Kamal Ahmed Mostafa

机构信息

Department of Anesthesia, Faculty of Medicine, Beni Suef University, Cairo, Egypt.

出版信息

Exp Clin Transplant. 2015 Dec;13(6):550-5.

Abstract

OBJECTIVES

The increased number of liver transplants in Egypt has increased the focus on perioperative complications in live donors. An important but not yet well-investigated complication is electrolyte disturbances, which are common in such patients, need intervention, and affect the outcome. We retrospectively analyzed data of perioperative calcium, magnesium, and phosphorus levels in live liver donors at our center.

MATERIALS AND METHODS

We collected perioperative laboratory results from 44 living donors for liver transplant who were at our center from February 2009 to August 2013. We analyzed results of perioperative calcium, magnesium, and phosphorus levels before transplant, on the day of transplant (defined as day 0), and at 1 and 2 days after the surgical procedure.

RESULTS

Mean serum calcium level was 2.31 mmol/L before transplant, 1.97 mmol/L on day 0, and 1.99 mmol/L on day 1, and 2.05 mmol/L on day 2 after transplant. Serum calcium level was significantly reduced at day 0 and on postoperative days 1 and 2 (P < .0001). Mean magnesium level was 0.8 mmol/L before transplant, 0.58 mmol/L on day 0, and 0.83 mmol/L on day 1, and 0.79 mmol/L on day 2 after the surgical procedure. The day 0 level was significantly reduced versus before transplant (P < .0001). Mean phosphorus level was 1.23 mmol/L before transplant, 1.11 mmol/L on day 0, and 0.97 mmol/L on day 1, and 0.76 mmol/L on day 2 after transplant, with significant declines on day 0 and on postoperative days 1 and 2 (P < .0001).

CONCLUSIONS

Living liver donors showed significantly decreased levels of calcium and phosphorus on day 0 and on postoperative days 1 and 2, whereas magnesium level was significantly decreased on day 0 only.

摘要

目的

埃及肝移植数量的增加使得对活体供者围手术期并发症的关注增多。电解质紊乱是一种重要但尚未得到充分研究的并发症,在这类患者中很常见,需要进行干预,并且会影响预后。我们回顾性分析了本中心活体肝供者围手术期钙、镁和磷水平的数据。

材料与方法

我们收集了2009年2月至2013年8月在本中心接受肝移植的44名活体供者的围手术期实验室检查结果。我们分析了移植前、移植当天(定义为第0天)以及手术后第1天和第2天的围手术期钙、镁和磷水平的检查结果。

结果

移植前血清钙平均水平为2.31 mmol/L,第0天为1.97 mmol/L,第1天为1.99 mmol/L,移植后第2天为2.05 mmol/L。血清钙水平在第0天以及术后第1天和第2天显著降低(P <.0001)。移植前镁平均水平为0.8 mmol/L,第0天为0.58 mmol/L,第1天为0.83 mmol/L,手术后第2天为0.79 mmol/L。与移植前相比,第0天的水平显著降低(P <.0001)。移植前磷平均水平为1.23 mmol/L,第0天为1.11 mmol/L,第1天为0.97 mmol/L,移植后第2天为0.76 mmol/L,在第0天以及术后第1天和第2天显著下降(P <.0001)。

结论

活体肝供者在第0天以及术后第1天和第2天钙和磷水平显著降低,而镁水平仅在第0天显著降低。

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