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[Cloning and study of the function of recA-like gene of Yersinia pestis in Escherichia coli cells].

作者信息

Suchkov I Iu, Mishan'kin B N

出版信息

Mol Gen Mikrobiol Virusol. 1989 May(5):34-9.

PMID:2664489
Abstract

A 2 kb fragment of Yersinia pestis genome cloned in Escherichia coli cells of the strain HB101 contains a gene able to complement the recA-dependent deficiency of E. coli cells in UV-resistance, resistance to alkylating agents, UV- and MNNG-induced mutability. Cellular capability for homologous recombination in crosses with HfrH donor, derepressed synthesis of bacteriocins (colicin E1 and pesticin 1) is also complemented by the fragment in E. coli recA-strains. The obtained data suggest the functional homology of the cloned recA-like gene product with the product of E. coli recA-gene.

摘要

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