经眼多普勒和视神经鞘直径监测以检测颅内高压。
Transocular Doppler and optic nerve sheath diameter monitoring to detect intracranial hypertension.
作者信息
Karami Mehdi, Shirazinejad Somayeh, Shaygannejad Vahid, Shirazinejad Zahra
机构信息
Department of Radiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Isfahan Neurosciences Research Center, Alzahra Hospital, Isfahan, Iran ; Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
Adv Biomed Res. 2015 Oct 22;4:231. doi: 10.4103/2277-9175.167900. eCollection 2015.
BACKGROUND
Increases in intracranial pressure (ICP) require a rapid recognition to allow for adequate treatments. The aim of this study was to determine whether transocular Doppler and optic nerve sheath diameter (ONSD) monitoring could reliably identify increases in ICP.
MATERIALS AND METHODS
This is a cross-sectional case-control study, which was carried out on 2013. Subjects were chosen from patients who admitted to the neurology and neurosurgery departments and the intensive care unit of Alzahra Hospital (Isfahan, Iran). To measure the ICP, the authors used ultrasound to measure the diameter of the optic nerve sheath and transocular Doppler (TOD) to measure blood flew velocity in ophthalmic artery (OA) and ophthalmic vein (OV) in both groups.
RESULTS
The mean of ONSD was 4.8 mm (SD 0.77) in patients with raised ICP and 3.2 mm (SD 0.3) in healthy volunteers which was significant (P < 0.001). The mean (SD) of TOD parameters were also significantly more in OA and OV of patients with raised ICP.
CONCLUSION
Ultrasound methods has been proposed as an alternative safe technique for invasive ICP measuring methods.
背景
颅内压（ICP）升高需要迅速识别以便进行适当治疗。本研究的目的是确定经眼多普勒和视神经鞘直径（ONSD）监测能否可靠地识别ICP升高。
材料与方法
这是一项横断面病例对照研究，于2013年开展。研究对象选自阿尔扎赫拉医院（伊朗伊斯法罕）神经科、神经外科和重症监护病房的患者。为测量ICP，作者在两组中均使用超声测量视神经鞘直径，并使用经眼多普勒（TOD）测量眼动脉（OA）和眼静脉（OV）中的血流速度。
结果
ICP升高患者的ONSD平均值为4.8 mm（标准差0.77），健康志愿者为3.2 mm（标准差0.3），差异有统计学意义（P < 0.001）。ICP升高患者的OA和OV中TOD参数的平均值（标准差）也显著更高。
结论
超声方法已被提议作为有创ICP测量方法的一种替代安全技术。
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