a Department of Ophthalmology , Seoul National University College of Medicine , Seoul , Korea.
b Department of Ophthalmology , Seoul National University Hospital Healthcare System Gangnam Center , Seoul , Korea.
Ocul Immunol Inflamm. 2016 Dec;24(6):653-659. doi: 10.3109/09273948.2015.1063668. Epub 2015 Dec 8.
To assess discrepancies between fluorescein angiography (FA) and optical coherence tomography (OCT) findings for macular edema (ME) in intermediate uveitis, and investigate treatment response differences corresponding to the discrepant patterns.
Discrepant results for ME detection between FA and OCT were evaluated. After 6 months, differences in treatment responses were analyzed.
Discrepant findings for ME were found in 21 (44%) of 48 eyes. The best-corrected visual acuity significantly improved after treatment in the concordant group but not in the discrepant groups. Central retinal thickness significantly decreased after treatment in the FA+/OCT+ and FA-/OCT+ groups but not in the FA+/OCT- group. Disease duration was significantly longer in the FA+/OCT- group than in the other groups.
Discrepancies in FA and OCT findings for ME were common in patients with intermediate uveitis. Our results suggest that treatment outcomes may differ according to the discrepant patterns.
评估中间葡萄膜炎性黄斑水肿(ME)中荧光素血管造影(FA)和光相干断层扫描(OCT)结果之间的差异,并研究与这些差异模式相对应的治疗反应差异。
评估 FA 和 OCT 对 ME 检测的差异结果。6 个月后,分析治疗反应的差异。
在 48 只眼中,有 21 只(44%)存在 ME 的不一致发现。在 FA+/OCT+和 FA-/OCT+组中,中央视网膜厚度(CRT)在治疗后显著降低,但在 FA+/OCT-组中没有降低。在 FA+/OCT-组中,疾病持续时间明显长于其他组。
中间葡萄膜炎患者 FA 和 OCT 对 ME 的检测结果存在差异。我们的结果表明,根据不一致模式,治疗结果可能会有所不同。