原儿茶酸的药理活性

PHARMACOLOGICAL ACTIVITIES OF PROTOCATECHUIC ACID.

作者信息

Khan Abida Kalsoom, Rashid Rehana, Fatima Nighat, Mahmood Sadaf, Mir Sadullah, Khan Sara, Jabeen Nyla, Murtaza Ghulam

出版信息

Acta Pol Pharm. 2015 Jul-Aug;72(4):643-50.

Abstract

Protocatechuic acid (3,4-dihydroxybenzoic acid, PCA) is a simple phenolic acid. It is found in a large variety of edible plants and possesses various pharmacological activities. This article aims to review the modern trends in phytochemical isolation and extraction of PCA from plants and other natural resources. Moreover, this article also encompasses pharmacological and biological activities of PCA. It is well known to have anti-inflammatory, antioxidant, anti-hyperglycemia, antibacterial, anticancer, anti-ageing, anti-athro- genic, anti-tumoral, anti-asthma, antiulcer, antispasmodic and neurological properties.

摘要

原儿茶酸（3,4-二羟基苯甲酸，PCA）是一种简单的酚酸。它存在于多种可食用植物中，并具有多种药理活性。本文旨在综述从植物和其他自然资源中分离提取PCA的现代植物化学趋势。此外，本文还涵盖了PCA的药理和生物学活性。众所周知，它具有抗炎、抗氧化、抗高血糖、抗菌、抗癌、抗衰老、抗动脉粥样硬化、抗肿瘤、抗哮喘、抗溃疡、解痉和神经方面的特性。