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本文引用的文献

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Effect of an invasive strategy on outcome in patients ≥75 years of age with non-ST-elevation acute coronary syndrome.侵入性治疗策略对≥75岁非ST段抬高型急性冠状动脉综合征患者预后的影响。
Am J Cardiol. 2015 Mar 1;115(5):576-80. doi: 10.1016/j.amjcard.2014.12.005. Epub 2014 Dec 18.
2
Favorable outcome of hematopoietic stem cell transplantation using a targeted once-daily intravenous busulfan-fludarabine-etoposide regimen in pediatric and infant acute lymphoblastic leukemia patients.在儿童和婴幼儿急性淋巴细胞白血病患者中,使用靶向每日一次静脉注射白消安-氟达拉滨-依托泊苷方案进行造血干细胞移植的良好结果。
Biol Blood Marrow Transplant. 2015 Jan;21(1):190-5. doi: 10.1016/j.bbmt.2014.09.013. Epub 2014 Sep 22.
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Acute myocardial infarction.急性心肌梗死
Crit Care Clin. 2014 Jul;30(3):341-64. doi: 10.1016/j.ccc.2014.03.010.
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Percutaneous coronary intervention in treatment of multivessel coronary artery disease in patients with non-ST-segment elevation acute coronary syndrome.经皮冠状动脉介入治疗非ST段抬高型急性冠状动脉综合征患者的多支冠状动脉疾病
Postepy Kardiol Interwencyjnej. 2013;9(2):136-45. doi: 10.5114/pwki.2013.35448. Epub 2013 Jun 17.
5
Small changes in troponin T levels are common in patients with non-ST-segment elevation myocardial infarction and are linked to higher mortality.肌钙蛋白 T 水平的微小变化在非 ST 段抬高型心肌梗死患者中很常见,与更高的死亡率相关。
J Am Coll Cardiol. 2013 Oct 1;62(14):1231-1238. doi: 10.1016/j.jacc.2013.06.050. Epub 2013 Aug 7.
6
Association between angiographic complications and clinical outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention: an EARLY ACS (Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome) angiographic substudy.急性冠状动脉综合征患者行经皮冠状动脉介入治疗的血管造影并发症与临床结局的相关性:EARLY ACS(非 ST 段抬高急性冠状动脉综合征早期糖蛋白 IIb/IIIa 抑制)血管造影亚研究。
JACC Cardiovasc Interv. 2012 Sep;5(9):927-35. doi: 10.1016/j.jcin.2012.05.007.
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Management of acute coronary syndrome in South Africa: insights from the ACCESS (Acute Coronary Events - a Multinational Survey of Current Management Strategies) registry.南非急性冠状动脉综合征的管理:来自ACCESS(急性冠状动脉事件——当前管理策略的多国调查)注册研究的见解
Cardiovasc J Afr. 2012 Aug;23(7):365-70. doi: 10.5830/CVJA-2012-017. Epub 2012 Mar 13.
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Long term results of ST-segment elevation myocardial infarction versus non-ST-segment elevation myocardial infarction after off-pump coronary artery bypass grafting: propensity score matching analysis.非体外循环冠状动脉旁路移植术后 ST 段抬高型心肌梗死与非 ST 段抬高型心肌梗死的长期结果:倾向评分匹配分析。
J Korean Med Sci. 2012 Feb;27(2):153-9. doi: 10.3346/jkms.2012.27.2.153. Epub 2012 Jan 27.
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Multivessel vs single-vessel revascularization in patients with non-ST-segment elevation acute coronary syndrome and multivessel disease in the drug-eluting stent era.药物洗脱支架时代非 ST 段抬高型急性冠状动脉综合征伴多支血管病变患者的多支血管与单支血管血运重建。
Clin Cardiol. 2011 Mar;34(3):160-5. doi: 10.1002/clc.20858.
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Time to coronary angiography and outcomes among patients with high-risk non ST-segment elevation acute coronary syndromes: results from the SYNERGY trial.高危非ST段抬高型急性冠脉综合征患者进行冠状动脉造影的时间与预后:SYNERGY试验结果
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老年高危非ST段抬高型急性心肌梗死患者早期介入治疗时机的评估

Evaluation of early interventional treatment opportunity of the elderly & high-risk patients with non-ST segment elevation acute myocardial infarction.

作者信息

Liu Zhiqiang, Zhao Lipei, Li Yibo, Wang Zhifang, Liu Lingling, Zhang Fucheng

机构信息

Zhiqiang Liu, Department of Cardiology, Xinxiang Central Hospital, Xinxiang 453000, China.

Lipei Zhao, Department of Cardiology, Xinxiang Central Hospital, Xinxiang 453000, China.

出版信息

Pak J Med Sci. 2015 Sep-Oct;31(5):1053-6. doi: 10.12669/pjms.315.7881.

DOI:10.12669/pjms.315.7881
PMID:26648985
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4641254/
Abstract

OBJECTIVE

To investigate the effect of treatment on prognosis of patients with different timing of early interventional treatment for non-ST segment elevation acute myocardial infarction (NSTEMI).

METHODS

Forty two cases above 75 years old, diagnosed with high-risk on NSTEMI, were selected in cardiology department of Xinxiang central hospital. They were randomly divided into two groups: 22 in group A and 20 in group B. Group A was performed PCI surgery within 12 hours after the onset while group B from 12 to 24 hour after the onset. Major adverse cardiovascular events (including death, heart failure readmission rates after ischemia, malignant arrhythmias, again target vessel revascularization) and bleeding data were recorded at the three terms of hospitalization, one month after the onset and six months after the onset.

RESULTS

Angina, malignant arrhythmia and heart failure during hospitalization can be reduced after interventional treatment carried out within 12 hours after the onset. Readmission rates after ischemia, heart failure and the incidence of death can be significantly reduced after interventional treatment carried out during 1-6 month after the onset with no significant increase in bleeding rate.

CONCLUSION

In the treatment of elderly patients with NSTEMI, early interventional treatment is safe and effective.

摘要

目的

探讨不同时机早期介入治疗对非ST段抬高型急性心肌梗死(NSTEMI)患者预后的影响。

方法

选取新乡市中心医院心内科75岁以上诊断为高危NSTEMI的患者42例,随机分为两组:A组22例,B组20例。A组在发病12小时内行PCI手术,B组在发病12至24小时内行PCI手术。记录住院期间、发病后1个月和发病后6个月这三个时间点的主要不良心血管事件(包括死亡、缺血后心力衰竭再入院率、恶性心律失常、再次靶血管血运重建)及出血情况。

结果

发病12小时内行介入治疗可降低住院期间心绞痛、恶性心律失常及心力衰竭的发生率。发病1至6个月内行介入治疗可显著降低缺血后再入院率、心力衰竭及死亡率,且出血率无显著增加。

结论

在老年NSTEMI患者的治疗中,早期介入治疗安全有效。