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老年高危非ST段抬高型急性心肌梗死患者早期介入治疗时机的评估

Evaluation of early interventional treatment opportunity of the elderly & high-risk patients with non-ST segment elevation acute myocardial infarction.

作者信息

Liu Zhiqiang, Zhao Lipei, Li Yibo, Wang Zhifang, Liu Lingling, Zhang Fucheng

机构信息

Zhiqiang Liu, Department of Cardiology, Xinxiang Central Hospital, Xinxiang 453000, China.

Lipei Zhao, Department of Cardiology, Xinxiang Central Hospital, Xinxiang 453000, China.

出版信息

Pak J Med Sci. 2015 Sep-Oct;31(5):1053-6. doi: 10.12669/pjms.315.7881.

Abstract

OBJECTIVE

To investigate the effect of treatment on prognosis of patients with different timing of early interventional treatment for non-ST segment elevation acute myocardial infarction (NSTEMI).

METHODS

Forty two cases above 75 years old, diagnosed with high-risk on NSTEMI, were selected in cardiology department of Xinxiang central hospital. They were randomly divided into two groups: 22 in group A and 20 in group B. Group A was performed PCI surgery within 12 hours after the onset while group B from 12 to 24 hour after the onset. Major adverse cardiovascular events (including death, heart failure readmission rates after ischemia, malignant arrhythmias, again target vessel revascularization) and bleeding data were recorded at the three terms of hospitalization, one month after the onset and six months after the onset.

RESULTS

Angina, malignant arrhythmia and heart failure during hospitalization can be reduced after interventional treatment carried out within 12 hours after the onset. Readmission rates after ischemia, heart failure and the incidence of death can be significantly reduced after interventional treatment carried out during 1-6 month after the onset with no significant increase in bleeding rate.

CONCLUSION

In the treatment of elderly patients with NSTEMI, early interventional treatment is safe and effective.

摘要

目的

探讨不同时机早期介入治疗对非ST段抬高型急性心肌梗死(NSTEMI)患者预后的影响。

方法

选取新乡市中心医院心内科75岁以上诊断为高危NSTEMI的患者42例,随机分为两组:A组22例,B组20例。A组在发病12小时内行PCI手术,B组在发病12至24小时内行PCI手术。记录住院期间、发病后1个月和发病后6个月这三个时间点的主要不良心血管事件(包括死亡、缺血后心力衰竭再入院率、恶性心律失常、再次靶血管血运重建)及出血情况。

结果

发病12小时内行介入治疗可降低住院期间心绞痛、恶性心律失常及心力衰竭的发生率。发病1至6个月内行介入治疗可显著降低缺血后再入院率、心力衰竭及死亡率,且出血率无显著增加。

结论

在老年NSTEMI患者的治疗中,早期介入治疗安全有效。

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