Harrison William D, Lees Deborah, A'Court Jamie, Ankers Thomas, Harper Ian, Inman Dominic, Reed Mike R
Orthopaedic Department, Wansbeck General Hospital, Northumbria Healthcare Trust, Woodhorn Lane, Ashington, Northumberland NE63 9JJ, UK.
Surg Res Pract. 2015;2015:316817. doi: 10.1155/2015/316817. Epub 2015 Nov 16.
Background. An analgesic enhanced recovery (ER) protocol for patients with a hip fracture was introduced. It was hypothesised that the ER would reduce pain, length of stay and improve clinical outcomes. The protocol used intraoperative infiltration of levobupivacaine followed by ongoing wound infusions. Methods. Consecutive patients admitted to two hospitals were eligible for the ER protocol. Numerical Reporting Scale pain scores (0-10) were recorded alongside opiate requirements. 434 patients in the ER group (316 full ER, 90 partial ER, and 28 no ER) were compared to a control group (CG) of 100 consecutive patients managed with traditional opiate analgesia. Results. Mean opiate requirement was 49.2 mg (CG) versus 32.5 mg (ER). Pain scores were significantly reduced in the full ER group, p < 0.0001. Direct discharge home and mean acute inpatient stay were significantly reduced (p = 0.0031 and p < 0.0001, resp.). 30-day mortality was 15% (CG) versus 5.5% (ER), p = 0.0024. Conclusions. This analgesic ER protocol for patients with a hip fracture was safe and effective and was associated with reduced inpatient stay and mortality.
背景。针对髋部骨折患者引入了一种镇痛强化康复(ER)方案。据推测,该强化康复方案将减轻疼痛、缩短住院时间并改善临床结局。该方案采用术中左旋布比卡因浸润,随后持续伤口灌注。方法。两所医院收治的连续患者符合强化康复方案的条件。记录数字报告量表疼痛评分(0 - 10)以及阿片类药物需求量。将强化康复组的434例患者(316例完全强化康复、90例部分强化康复和28例未进行强化康复)与100例采用传统阿片类镇痛治疗的连续患者组成的对照组(CG)进行比较。结果。平均阿片类药物需求量在对照组为49.2毫克,而在强化康复组为32.5毫克。完全强化康复组的疼痛评分显著降低,p < 0.0001。直接出院回家的比例和平均急性住院时间均显著降低(分别为p = 0.0031和p < 0.0001)。30天死亡率在对照组为15%,而在强化康复组为5.5%,p = 0.0024。结论。这种针对髋部骨折患者的镇痛强化康复方案安全有效,且与住院时间缩短和死亡率降低相关。