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全膝关节置换术(TKA)患者的局部浸润镇痛可缩短住院时间并降低术后疼痛评分。

Local infiltration analgesia in TKA patients reduces length of stay and postoperative pain scores.

作者信息

Tripuraneni Krishna R, Woolson Steven T, Giori Nicholas J

机构信息

Department of Orthopedic Surgery, Stanford University, Stanford, California, USA.

出版信息

Orthopedics. 2011 Mar 11;34(3):173. doi: 10.3928/01477447-20110124-11.

Abstract

Numerous postoperative pain protocols exist for patients undergoing total knee arthroplasty (TKA). We compared the length of stay, early range of motion (ROM), and pain scores of a control group with a femoral nerve block to those of a group with femoral nerve block and local infiltration analgesia following TKA. In a consecutive series of patients undergoing primary TKA at a Veteran's Administration hospital, 40 patients (40 TKAs) who had local infiltration analgesia were compared to a historical group of 43 patients (43 TKAs) who had a long-acting femoral nerve block without local infiltration analgesia. Local infiltration analgesia consisted of intraoperative injection of 150 mL of 300 mg ropivacaine, 30 mg ketorolac, and 500 μg epinephrine using 50 mL into each of 3 areas: (1) posterior capsule, (2) medial and lateral capsule, and (3) anterior capsule and subcutaneous tissues. A 17-gauge intra-articular catheter was used to inject an additional 100 mg of ropivacaine on postoperative day 1. The control group had a single-shot femoral nerve block using 150 mg of ropivacaine with epinephrine. Mean length of stay for the local infiltration analgesia group compared to controls was 3.2±1.4 days vs 3.8±1.6 days, respectively (P=.03). No significant differences existed in average ROM (6 weeks), discharge hematocrit, transfusions, and temperature. Mean pain scores were lower in the local infiltration analgesia group on postoperative day 1 (P=.04), but not on postoperative day 2 or 3. Maximum visual analog scale scores (P<.01) were reduced in the local infiltration analgesia group. Our early experience with local infiltration analgesia demonstrated a significantly reduced length of stay due to decreased postoperative pain.

摘要

对于接受全膝关节置换术(TKA)的患者,有多种术后疼痛处理方案。我们比较了采用股神经阻滞的对照组与TKA术后采用股神经阻滞加局部浸润镇痛组的住院时间、早期活动范围(ROM)和疼痛评分。在一家退伍军人管理局医院连续进行初次TKA的一系列患者中,将40例接受局部浸润镇痛的患者(40例TKA)与43例接受长效股神经阻滞但未进行局部浸润镇痛的历史对照组患者(43例TKA)进行比较。局部浸润镇痛包括术中在3个区域各注入50 mL含150 mL 300 mg罗哌卡因、30 mg酮咯酸和500 μg肾上腺素的混合液:(1)后关节囊,(2)内外侧关节囊,(3)前关节囊和皮下组织。术后第1天使用17号关节内导管再注入100 mg罗哌卡因。对照组采用单次注射含肾上腺素的150 mg罗哌卡因进行股神经阻滞。与对照组相比,局部浸润镇痛组的平均住院时间分别为3.2±1.4天和3.8±1.6天(P = 0.03)。平均ROM(6周)、出院时血细胞比容、输血情况和体温无显著差异。局部浸润镇痛组术后第1天的平均疼痛评分较低(P = 0.04),但术后第2天和第3天无差异。局部浸润镇痛组的最大视觉模拟量表评分降低(P<0.01)。我们早期使用局部浸润镇痛的经验表明,由于术后疼痛减轻,住院时间显著缩短。

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