Ericsson I, Lindhe J
J Clin Periodontol. 1977 May;4(2):115-27. doi: 10.1111/j.1600-051x.1977.tb01891.x.
The experiments were performed in 15 dogs fed a diet which allowed dental plaque accumulation. A phase of experimental periodontal breakdown was initiated on day 0. After 210 days five dogs were sacrificed. In the remaining 10 dogs the periodontal pockets around the fourth lower premolars (4P and P4) were eliminated. During surgery a notch was prepared in the root at the level of the marginal termination of the alveolar bone in order to facilitate measurements in histological sections. From day 210 to day 450 the teeth of the animals were brushed twice daily. After 60 days of healing, i.e. on day 270, five of the dogs were sacrificed. Trauma from occlusion of the jiggling type was on day 270 produced in the P4 region of the remaining dogs by the installation of a cap splint and a bar device. The final five dogs were sacrificed on day 450. Following sacrifice, tissue sections comprising 3P, 4P, 1M and P3, P4, M1 were produced and subjected to microscopic analysis. The experiments revealed that, in the dog, forces produced by occlusal trauma are unable to induce a phase of progressive destruction of the periodontal tissues in tooth regions where the supporting tissues are markedly reduced but non-inflammatory.
实验在15只喂食允许牙菌斑积聚饮食的狗身上进行。在第0天开始实验性牙周破坏阶段。210天后，处死5只狗。在其余10只狗中，消除下颌第四前磨牙（4P和P4）周围的牙周袋。手术过程中，在牙槽骨边缘终止水平的牙根处制备一个切口，以便于在组织学切片中进行测量。从第210天到第450天，每天给动物的牙齿刷牙两次。愈合60天后，即第270天，处死5只狗。在其余狗的P4区域，通过安装帽式夹板和杆状装置，在第270天产生摆动型咬合创伤。最后5只狗在第450天处死。处死动物后，制作包括3P、4P、1M和P3、P4、M1的组织切片并进行显微镜分析。实验表明，在狗中，咬合创伤产生的力无法在支持组织明显减少但无炎症的牙齿区域诱导牙周组织进行性破坏阶段。
