Gomes Lívia M S, Silva Roberta G, Melo Monique, Silva Nayra N, Vanderlei Franciele M, Garner David M, de Abreu Luiz Carlos, Valenti Vitor E
Centro de Estudos do Sistema Nervoso Autônomo (CESNA), Departamento de Fonoaudiologia, Faculdade de Filosofia e Ciências, UNESP, Av. Hygino Muzzi Filho, 737, Marília, SP, 17.525-000, Brazil.
Laboratório de Disfagia (LADIS), Departamento de Fonoaudiologia, Faculdade de Filosofia e Ciências, UNESP, Marília, SP, Brazil.
Dysphagia. 2016 Apr;31(2):188-94. doi: 10.1007/s00455-015-9676-4. Epub 2015 Dec 9.
Swallowing-induced changes in heart rate have been recently reported. However, it is not apparent the responses of heart rate variability (HRV) elicited by effortful swallow maneuver. We investigated the acute effects of effortful swallowing maneuver on HRV. This study was performed on 34 healthy women between 18 and 35 years old. We assessed heart rate variability in the time (SDNN, RMSSD, and pNN50) and frequency (HF, LF, and LF/HF ratio) domains and, visual analysis through the Poincaré plot. The subjects remained at rest for 5 min during spontaneous swallowing and then performed effortful swallowing for 5 min. HRV was analyzed during spontaneous and effortful swallowing. We found no significant differences for SDNN, pNN50, RMSSD, HF in absolute units (ms(2)). There is a trend for increase of LF in absolute (p = 0.05) and normalized (p = 0.08) units during effortful swallowing. HF in normalized units reduced (p = 0.02) during effortful swallowing and LF/HF ratio (p = 0.03) increased during effortful swallowing. In conclusion effortful swallow maneuver in healthy women increased sympathetic cardiac modulation, indicating a cardiac overload.
最近有报道称吞咽会引起心率变化。然而，用力吞咽动作引起的心率变异性（HRV）反应并不明显。我们研究了用力吞咽动作对HRV的急性影响。本研究对34名年龄在18至35岁之间的健康女性进行。我们在时域（SDNN、RMSSD和pNN50）和频域（HF、LF和LF/HF比值）评估心率变异性，并通过庞加莱图进行视觉分析。受试者在自主吞咽过程中静息5分钟，然后进行5分钟的用力吞咽。在自主吞咽和用力吞咽过程中对HRV进行分析。我们发现，SDNN、pNN50、RMSSD、HF的绝对单位（ms(2)）无显著差异。在用力吞咽过程中，LF的绝对单位（p = 0.05）和标准化单位（p = 0.08）有增加趋势。在用力吞咽过程中，HF的标准化单位降低（p = 0.02），LF/HF比值增加（p = 0.03）。总之，健康女性的用力吞咽动作增加了交感神经对心脏的调节，表明心脏负荷过重。
