Wu Chun-Ying, Lin Jaw-Town
Division of Gastroenterology, Taichung Veterans General Hospital, Taichung, Taiwan; Faculty of Medicine and Graduate Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Public Health and Graduate Institute of Clinical Medicine, China Medical University, Taichung, Taiwan; National Institute of Cancer Research, National Health Research Institutes, Miaoli, Taiwan; Department of Life Sciences, National Chung-Hsing University, Taichung, Taiwan.
School of Medicine, Fu Jen Catholic University, Taipei, Taiwan; Department of Internal Medicine, E-Da Hospital/I-Shou University, Kaohsiung, Taiwan; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan.
Best Pract Res Clin Gastroenterol. 2015 Dec;29(6):843-53. doi: 10.1016/j.bpg.2015.09.016. Epub 2015 Sep 26.
Digestive cancers are a major health burden in Asia. Due to the presence of similar "infection-inflammation-cancer" pathways in the carcinogenesis process, eradicating infective pathogens or attenuating relevant inflammatory signaling pathways may reduce digestive cancer incidences and improve patient outcomes. The aim of this paper is to review the recent evidence regarding the epidemiology of three major digestive cancers in Asia: stomach cancer, liver cancer, and colorectal cancer. We focused on the incidence trends, the major etiologies, and especially the potential preventive strategies.
消化系统癌症是亚洲主要的健康负担。由于在致癌过程中存在相似的“感染-炎症-癌症”途径，根除感染性病原体或减弱相关炎症信号通路可能会降低消化系统癌症的发病率并改善患者预后。本文旨在综述亚洲三种主要消化系统癌症（胃癌、肝癌和结直肠癌）流行病学的最新证据。我们重点关注发病率趋势、主要病因，尤其是潜在的预防策略。
