Nagel Gabriele, Oberaigner Willi, Peter Raphael S, Ulmer Hanno, Concin Hans
Agency for Preventive and Social Medicine, Bregenz, Austria; Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.
Department of Clinical Epidemiology of the Tyrolean State Hospitals Ltd., Cancer Registry of Tyrol, TILAK GmbH, Innsbruck, Austria.
Cancer Epidemiol. 2015 Dec;39(6):812-8. doi: 10.1016/j.canep.2015.10.001. Epub 2015 Oct 18.
To describe the mammography screening program from 1989 to 2005 within a population-based prevention program in Austria and to appraise it according to recommended quality indicators.
From 01.01.1989 all women aged 40 years or older participating in the Vorarlberg Health Monitoring & Prevention Program (VHM&PP) was offered to undergo additionally a "screening mammography". Passive follow-up has been performed by record linkages with the Vorarlberg cancer registry and mortality statistics for information on outcome variables. Interval cancer rates have been estimated and the survival after breast cancer has been calculated by life table technique by examination period and age groups (40-49 years, 50-69 years).
Between 1989 and 2005 50,100 women aged 40 to 69 years participated in the program, of which 123,652 mammogram results have been collected. In the target population the participation rate was 65.1%. During median follow-up time 13.5 years and 633,342 person-years overall 665 invasive cancer and 87 ductal carcinoma in situ (11.6%) cases have been identified. Between 1996 and 2004 the detection rates were 239.9 per 100.000 among women aged 40-49 years and 543.2 per 100,000 among women aged 50-69 years. The rates for interval cancers were 160.4 and 277.4 per 100 000 negative screens, respectively. During median follow-up of 13.5 years 165 deaths occurred with no difference in survival between patients with interval and screen detected cancers.
A mammography screening program has been performed between 1989 and 2005 in Vorarlberg. Till 2005 most quality indicators improved and met the EU-recommendations suggesting that alternative approaches to organized mammography screening based on routine data should be explored.
描述1989年至2005年奥地利一项基于人群的预防项目中的乳腺钼靶筛查计划,并根据推荐的质量指标对其进行评估。
自1989年1月1日起,向所有参加福拉尔贝格健康监测与预防项目(VHM&PP)的40岁及以上女性额外提供“乳腺钼靶筛查”。通过与福拉尔贝格癌症登记处和死亡率统计数据进行记录链接,对结局变量信息进行被动随访。估计了间期癌症发生率,并通过生命表技术按检查期和年龄组(40 - 49岁、50 - 69岁)计算了乳腺癌后的生存率。
1989年至2005年期间,50100名40至69岁女性参与了该项目,共收集到123652份乳腺钼靶检查结果。目标人群中的参与率为65.1%。在中位随访时间13.5年和633342人年期间,共确诊665例浸润性癌和87例原位导管癌(11.6%)。1996年至2004年期间,40 - 49岁女性的检出率为每100000人239.9例,50 - 69岁女性的检出率为每100000人543.2例。间期癌症发生率分别为每100000次阴性筛查160.4例和277.4例。在13.5年的中位随访期间,发生了165例死亡,间期癌症患者和筛查发现癌症患者的生存率无差异。
1989年至2005年期间在福拉尔贝格实施了乳腺钼靶筛查计划。到2005年,大多数质量指标有所改善并符合欧盟建议,这表明应探索基于常规数据的有组织乳腺钼靶筛查的替代方法。