Vavilova T P, Petrovich Iu A, Barer G M, Tolmacheva I I
Stomatologiia (Mosk). 1989 Jan-Feb;68(1):24-6.
In patients with parodontitis varying in severity, nitrites content and nitrate reductase activity were measured in the oral and gingival fluids (OF, GF). In patients, as compared to control subjects, OF displayed a tendency to reduce nitrates concentration which was lowered fourfold in exacerbations. Nitrate reductase activity was distinctly reduced in remissions of light and mild parodintitis, and increased in exacerbations. GF showed a low nitrite content with its nitrate reductase activity varying from 0 to 1.66 mumol/min per 1 ml. These levels were not different in patients and control group. The data indicate different states of oral homeostasis in parodontitis varying in severity.
在患有不同严重程度牙周炎的患者中,测量了口腔和龈沟液(OF、GF)中的亚硝酸盐含量和硝酸盐还原酶活性。与对照组相比,患者的OF呈现出硝酸盐浓度降低的趋势,在病情加重时降低了四倍。在轻度和中度牙周炎缓解期,硝酸盐还原酶活性明显降低,而在病情加重时升高。GF显示出低亚硝酸盐含量,其硝酸盐还原酶活性为每1毫升0至1.66微摩尔/分钟。这些水平在患者和对照组中没有差异。数据表明不同严重程度的牙周炎患者口腔内稳态处于不同状态。