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[地库林对五种试验对象致突变活性的比较研究]

[Comparative study of the mutagenic activity of dicurin on five test-objects].

作者信息

Kurinnyĭ A I, Masnik L I, L'vova T S

出版信息

Tsitol Genet. 1989 Jan-Feb;23(1):9-13.

PMID:2665249
Abstract

Mutagenic activity of dicourol belonging to coumarol derivatives has been studied on 5 test-objects (mice, cultivated lymphocytes of human blood, yeast-saccharomycetes, Tradescantia, Crepis). Results of investigations allowed attributing dicourol to highly hazardous mutagens. In this connection it is admitted unadvisable to enforce it into agricultural practice. The tested objects differ in their dicourol mutagenic sensibility as follows: cultivated lymphocytes of human blood - Tradescantia - yeast - Crepis - mice.

摘要

已在5种试验对象(小鼠、人血培养淋巴细胞、酵母-酿酒酵母、紫露草、还阳参)上研究了香豆醇衍生物双香豆醇的诱变活性。研究结果表明双香豆醇属于高危险性诱变剂。鉴于此,不宜将其应用于农业生产实践。受试对象对双香豆醇的诱变敏感性差异如下:人血培养淋巴细胞>紫露草>酵母>还阳参>小鼠。

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